دورية أكاديمية
Trained Immunity as an Adaptive Branch of Innate Immunity
| العنوان: | Trained Immunity as an Adaptive Branch of Innate Immunity |
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| المؤلفون: | Vaclav Vetvicka, Petr Sima, Luca Vannucci |
| المصدر: | International Journal of Molecular Sciences, Vol 22, Iss 19, p 10684 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | trained immunity, glucan, macrophages, NK cells, basophils, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | The concept of trained immunity has become one of the most interesting and potentially commercially and clinically relevant ideas of current immunology. Trained immunity is realized by the epigenetic reprogramming of non-immunocompetent cells, primarily monocytes/macrophages and natural killer (NK) cells, and is less specific than adaptive immunity; therefore, it may cross-protect against other infectious agents. It remains possible, however, that some of the observed changes are simply caused by increased levels of immune reactions resulting from supplementation with immunomodulators, such as glucan. In addition, the question of whether we can talk about trained immunity in cells with a life span of only few days is still unresolved. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/22/19/10684; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms221910684 |
| URL الوصول: | https://doaj.org/article/050f4c8d4edb4fa9bcbb69a0f4f8c0cf |
| رقم الأكسشن: | edsdoj.050f4c8d4edb4fa9bcbb69a0f4f8c0cf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms221910684 |