دورية أكاديمية
Effects of Antiepileptic Drugs on Bone Density and Metabolism
العنوان: | Effects of Antiepileptic Drugs on Bone Density and Metabolism |
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المؤلفون: | Zeynep AYDIN ÖZEMİR, Ayşe Destina YALÇIN |
المصدر: | Archives of Epilepsy, Vol 23, Iss 1, Pp 1-6 (2017) |
بيانات النشر: | Galenos Yayinevi, 2017. |
سنة النشر: | 2017 |
المجموعة: | LCC:Neurology. Diseases of the nervous system LCC:Medicine |
مصطلحات موضوعية: | antiepileptic drugs, calcium metabolism, decrease in bone mineral density, Neurology. Diseases of the nervous system, RC346-429, Medicine |
الوصف: | Many studies have demonstrated that both classic (e.g., phenobarbital, carbamazepine, valproate) and new antiepileptic drugs (e.g., oxcarbazepine, gabapentin) decrease bone metabolism. Abnormalities in calcium metabolism often occur on inducing the cytochrome P450 enzyme system, thus decreasing vitamin D levels. However, the reason some antiepileptic drugs that suppress (e.g., valproate) or have no effect on this system also affect vitamin D metabolism is not known. This study explored the effect of classic and new antiepileptic drugs on bone health and calcium metabolism. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2792-0550 |
Relation: | http://archepilepsy.org/archives/archive-detail/article-preview/effects-of-antiepileptic-drugs-on-bone-density-and/54987; https://doaj.org/toc/2792-0550 |
DOI: | 10.14744/epilepsi.2016.93723 |
URL الوصول: | https://doaj.org/article/0548d3a6218642e0ad71b46c65360474 |
رقم الأكسشن: | edsdoj.0548d3a6218642e0ad71b46c65360474 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 27920550 |
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DOI: | 10.14744/epilepsi.2016.93723 |