دورية أكاديمية
Advances in technology for the laboratory diagnosis of individuals with HIV/AIDS coinfected with Mycobacterium tuberculosis
| العنوان: | Advances in technology for the laboratory diagnosis of individuals with HIV/AIDS coinfected with Mycobacterium tuberculosis |
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| المؤلفون: | Jin Sun, Xiaoxu Han, Hongxia Yan, Xin Zhang, Taiyi Jiang, Tong Zhang, Hao Wu, Grigory Kaminskiy, Yingmin Ma, Eduard Karamov, Bin Su |
| المصدر: | Biosafety and Health, Vol 6, Iss 3, Pp 133-142 (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Infectious and parasitic diseases LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Human immunodeficiency virus (HIV) /Mycobacterium tuberculosis (MTB) coinfection, Mycobacterium tuberculosis (MTB), Early diagnosis, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270 |
| الوصف: | The high morbidity and mortality rate of individuals with human immunodeficiency virus (HIV) / acquired immunodeficiency syndrome (AIDS) coinfected with Mycobacterium tuberculosis (MTB) is a tough challenge for current global tuberculosis prevention and control efforts. HIV/MTB coinfection is more complex than a single infection, and the interaction between the two diseases aggravates the deterioration caused by the disease, resulting in increased hospitalizations and deaths. Rapid screening and early diagnosis facilitate the timely initiation of anti-tuberculosis treatment in HIV/MTB coinfected individuals, thereby reducing transmission and the incidence of adverse prognoses. To date, pathogenic detection has remained the gold standard for diagnosing tuberculosis, but its sensitivity and specificity are greatly affected by the body's immune status, which limits its application in the diagnosis of HIV/MTB coinfection. Recently, immunology and molecular detection technology has developed rapidly. New detection technologies, such as interferon-γ release assays, interferon-gamma inducible protein 10, and GeneXpert MTB/RIF assay have overcome the limitations of traditional detection methods, significantly improved the sensitivity and specificity of tuberculosis diagnosis, and brought new hope to the detection of HIV/MTB coinfection. In this article, the principle, scope of application, and latest research progress of relevant detection methods are reviewed to provide a reference for the early diagnosis of HIV/MTB coinfection. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2590-0536 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2590053624000533; https://doaj.org/toc/2590-0536 |
| DOI: | 10.1016/j.bsheal.2024.04.003 |
| URL الوصول: | https://doaj.org/article/075912221d9b4fc0899ebaa8599cf237 |
| رقم الأكسشن: | edsdoj.075912221d9b4fc0899ebaa8599cf237 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25900536 |
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| DOI: | 10.1016/j.bsheal.2024.04.003 |