Estrogen receptor α drives pro-resilient transcription in mouse models of depression

التفاصيل البيبلوغرافية
العنوان:	Estrogen receptor α drives pro-resilient transcription in mouse models of depression
المؤلفون:	Zachary S. Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M. Walker, Eric M. Parise, Marine Salery, Michael E. Cahill, Georgia E. Hodes, Madeline L. Pfau, Hope Kronman, Peter J. Hamilton, Orna Issler, Benoit Labonté, Ann E. Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J. Meaney, Scott J. Russo, Li Shen, Rosemary C. Bagot, Eric J. Nestler
المصدر:	Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
بيانات النشر:	Nature Portfolio, 2018.
سنة النشر:	2018
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Stress resilience is accompanied by broad changes in gene expression. This study shows that estrogen receptor α (ERα) is a key upstream regulator of these changes in the nucleus accumbens, and that overexpression of ERα increases behavioral resilience via a sex-specific transcriptional mechanism.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-018-03567-4
URL الوصول:	https://doaj.org/article/ece077944a9741a483557c3a2aad83ec
رقم الأكسشن:	edsdoj.077944a9741a483557c3a2aad83ec
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-018-03567-4