Left ventricular myxomas are extremely rare. We report the transmitral approach through right anterolateral minithoracotomy for excision of a left ventricular septal myxoma in a 72-year-old asymptomatic man. A postoperative course was uneventful without arrhythmia. [Arch Clin Exp Surg 2012; 1(3.000): 188-190]