Ascorbic Acid-Initiated Tandem Radical Cyclization of N-Arylacrylamides to Give 3,3-Disubstituted Oxindoles

التفاصيل البيبلوغرافية
العنوان:	Ascorbic Acid-Initiated Tandem Radical Cyclization of N-Arylacrylamides to Give 3,3-Disubstituted Oxindoles
المؤلفون:	Sheng Liu, Pi Cheng, Wei Liu, Jian-Guo Zeng
المصدر:	Molecules, Vol 20, Iss 9, Pp 15631-15642 (2015)
بيانات النشر:	MDPI AG, 2015.
سنة النشر:	2015
المجموعة:	LCC:Organic chemistry
مصطلحات موضوعية:	N-arylacrylamides, 3,3-disubstituted oxindoles, tandem cyclization, ascorbic acid, 4-nitroaniline, Organic chemistry, QD241-441
الوصف:	An ascorbic acid-promoted and metal-free tandem room temperature cyclization of N-arylacrylamides with 4-nitrobenzenediazonium generated in situ was developed. This reaction proceeds smoothly through a radical mechanism and provides an environmentally friendly alternative approach to biologically active 3-alkyl-3-benzyloxindoles, avoiding the use of excess oxidants and light irradiation.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1420-3049
Relation:	http://www.mdpi.com/1420-3049/20/9/15631; https://doaj.org/toc/1420-3049
DOI:	10.3390/molecules200915631
URL الوصول:	https://doaj.org/article/07b9d9e3977d4438a6685cd305b28bf1
رقم الأكسشن:	edsdoj.07b9d9e3977d4438a6685cd305b28bf1
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	14203049
DOI:	10.3390/molecules200915631