دورية أكاديمية
أعرض في EDS

Multimarker risk stratification approach and cardiovascular outcomes in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention

التفاصيل البيبلوغرافية
العنوان: Multimarker risk stratification approach and cardiovascular outcomes in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention
المؤلفون: Vimal Mehta, Rishi Sukhija, Pratishtha Mehra, Anuj Goyal, Jamal Yusuf, Bhawna Mahajan, V.K. Gupta, Sanjay Tyagi, Chandrasekar Palaniswamy, Wilbert S. Aronow
المصدر: Indian Heart Journal, Vol 68, Iss 1, Pp 57-62 (2016)
بيانات النشر: Elsevier, 2016.
سنة النشر: 2016
المجموعة: LCC:Surgery
LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Biomarkers, Percutaneous coronary intervention, Periprocedural myocardial infarction, Major adverse cardiovascular event, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Aims: We studied the utility of multimarker risk stratification approach to predict cardiovascular outcomes in patients with stable coronary artery disease, undergoing elective percutaneous coronary intervention (PCI). Methods: We prospectively evaluated 302 consecutive patients with stable coronary artery disease and normal CPK-MB and cardiac troponin T levels, and who underwent elective PCI at our institution. The following cardiac biomarkers were measured before and between 12 and 24 h post-procedure: CK-MB, cardiac troponin T, hs-CRP, and NT-ProBNP. Patients were followed up for a minimum of 6 months. Results: Post-PCI, CPK-MB levels were elevated but below myocardial infarction (MI) range in 70 patients (23%), and in the MI range in 6 patients (2%). Troponin T levels were detectable but below the 99th percentile (microleak) in 32 patients (10.6%) and elevated above the 99th percentile (periprocedural MI) in 104 patients (34.4%). At 9 months’ follow-up, 1% died, 2% had stable angina, 10.3% had non-fatal MI, and 87.7% remained asymptomatic. There was no significant difference in clinical events among groups stratified by elevation of one biomarker or multiple biomarkers. Conclusion: Single or multiple biomarker strategy in patients with normal baseline biomarkers failed to predict major cardiac events after PCI over medium-term follow-up.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0019-4832
Relation: http://www.sciencedirect.com/science/article/pii/S0019483215002606; https://doaj.org/toc/0019-4832
DOI: 10.1016/j.ihj.2015.06.034
URL الوصول: https://doaj.org/article/e07d685ba0494cbe8daff303715c447a
رقم الأكسشن: edsdoj.07d685ba0494cbe8daff303715c447a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00194832
DOI:10.1016/j.ihj.2015.06.034