دورية أكاديمية
Stereotactic radiofrequency ablation as a valid first-line treatment option for hepatocellular adenomas
| العنوان: | Stereotactic radiofrequency ablation as a valid first-line treatment option for hepatocellular adenomas |
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| المؤلفون: | Gregor Laimer, Peter Schullian, Yannick Scharll, Daniel Putzer, Gernot Eberle, Georg Oberhuber, Reto Bale |
| المصدر: | International Journal of Hyperthermia, Vol 39, Iss 1, Pp 780-787 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medical technology |
| مصطلحات موضوعية: | Radiofrequency ablation, liver neoplasms, tomography, X-ray computed, treatment outcome, Medical technology, R855-855.5 |
| الوصف: | Objectives This study aimed to assess the safety and efficacy of stereotactic radiofrequency ablation (SRFA) in patients with hepatocellular adenomas (HCA).Methods Retrospective analyses of all patients referred for SRFA treatment at our institution between January 2010 and October 2020 revealed 14 patients (10 women; mean age 34.4 [range, 17–73 years]) with 38 HCAs treated through 18 ablation sessions. Ablations were considered successful if a safety margin >5 mm was achieved. Demographic, interventional, and outcome data were collected and analyzed. Primary and secondary technical efficacy rates were assessed based on follow-up images consisting of contrast-enhanced CT or MR scans.Results The mean tumor size was 22 mm (range, 7–75 mm). Overall, 37/38 (97.4%) tumors were successfully ablated at the initial SRFA (primary efficacy rate of 97.4%). The median follow-up duration was 49.6 months. No deaths or adenoma-related complications (hemorrhage or malignant transformation) were observed. Disease-free survival rates at 1, 3, and 5 years from the date of the first SRFA were 100%, 85.8%, and 85.8%, respectively. Two patients developed new distant tumors retreated with consecutive re-ablation. No major complications occurred during any of the 18 ablation sessions.Conclusions Percutaneous thermal ablation is efficient in the treatment of HCAs and may thus be considered a valid first-line treatment option. In addition, SRFA allows for an effective, minimally invasive treatment of large and multiple hepatic tumors within one session. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 02656736 1464-5157 0265-6736 |
| Relation: | https://doaj.org/toc/0265-6736; https://doaj.org/toc/1464-5157 |
| DOI: | 10.1080/02656736.2022.2082562 |
| URL الوصول: | https://doaj.org/article/ea08166464714dffb864958368c8149b |
| رقم الأكسشن: | edsdoj.08166464714dffb864958368c8149b |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 02656736 14645157 |
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| DOI: | 10.1080/02656736.2022.2082562 |