دورية أكاديمية
Lamotrigine-induced hypersensitivity syndrome with histologic features of cd30+ lymphoma
العنوان: | Lamotrigine-induced hypersensitivity syndrome with histologic features of cd30+ lymphoma |
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المؤلفون: | Farid Stephan, Roger Haber, Elio Kechichian, Francois Kamar |
المصدر: | Indian Journal of Dermatology, Vol 61, Iss 2, Pp 235-235 (2016) |
بيانات النشر: | Wolters Kluwer Medknow Publications, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Dermatology |
مصطلحات موضوعية: | Drug rash with eosinophilia and systemic symptoms, hypersensitivity syndrome, lamotrigine, lymphoma, pseudolymphoma, Dermatology, RL1-803 |
الوصف: | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome or drug-induced hypersensitivity syndrome (DIHS) is a severe adverse drug reaction. It can present with clinical, paraclinical, and histological findings mimicking skin and/or systemic lymphomas. We report the first case of a lamotrigine-induced DRESS with histologic features of a cutaneous CD30+ lymphoma. The patient responded well to a tapering course of oral steroids. This case highlights the atypical presentation of a lamotrigine-induced DRESS/DIHS in the presence of a cutaneous and a lymph node CD30 + lymphocytic infiltrate mimicking systemic lymphoma. Pathologists and clinicians must be aware of this “lymphomatous” presentation of drug reactions. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0019-5154 1998-3611 |
Relation: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2016;volume=61;issue=2;spage=235;epage=235;aulast=Stephan; https://doaj.org/toc/0019-5154; https://doaj.org/toc/1998-3611 |
DOI: | 10.4103/0019-5154.177784 |
URL الوصول: | https://doaj.org/article/0888f89d92e64416b2f7ea4e761b2fe1 |
رقم الأكسشن: | edsdoj.0888f89d92e64416b2f7ea4e761b2fe1 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 00195154 19983611 |
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DOI: | 10.4103/0019-5154.177784 |