دورية أكاديمية
Efficiency of Protective Interventions on Irinotecan-Induced Diarrhea: A Systematic Review and Meta-Analysis
العنوان: | Efficiency of Protective Interventions on Irinotecan-Induced Diarrhea: A Systematic Review and Meta-Analysis |
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المؤلفون: | Yanxi He MB, Lili Wu MM, Xiaoyi Qi MD,PhD, Xuan Wang MM, Bing He BS, Wei Zhang MM, Wenjing Zhao MB, Mingming Deng MB, Xia Xiong MB, Yu Wang MB, Sicheng Liang PhD |
المصدر: | Integrative Cancer Therapies, Vol 23 (2024) |
بيانات النشر: | SAGE Publishing, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Background: Irinotecan is widely used in the treatment of various solid tumors, but the adverse effects from it, especially diarrhea, limit its use. Several clinical trials of prophylactic treatment of irinotecan-induced diarrhea (IID) have been ongoing, and some of the data are controversial. This encouraged us to conduct a meta-analysis of the effects of interventions on preventing IID. Method: This systematic review was conducted based on the PRISMA statement. We performed literature searches from PubMed, Web of Science, Embase, and Cochrane Library. The number registered in PROSPERO is CRD42022368633. After searching 1034 articles in the database and references, 8 studies were included in this meta-analysis. Result: The RR of high-grade diarrhea and all-grade diarrhea were 0.31 ( I 2 = 51%, 95% CI: 0.14-0.69; P = .004) and .76 ( I 2 = 65%, 95% CI: 0.62-0.93; P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1552-695X 15347354 |
Relation: | https://doaj.org/toc/1552-695X |
DOI: | 10.1177/15347354241242110 |
URL الوصول: | https://doaj.org/article/0890d19bb02a467b91152579d92225a2 |
رقم الأكسشن: | edsdoj.0890d19bb02a467b91152579d92225a2 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 1552695X 15347354 |
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DOI: | 10.1177/15347354241242110 |