دورية أكاديمية

Longitudinal comparison of bacterial pathogen seropositivity among wet market vendors in the Lao People's Democratic Republic

التفاصيل البيبلوغرافية
العنوان: Longitudinal comparison of bacterial pathogen seropositivity among wet market vendors in the Lao People's Democratic Republic
المؤلفون: Nilandone Senvanpan, Vilayouth Phimolsarnnousith, Sayaphet Rattanavong, Mayfong Mayxay, Daniel Reinharz, Amanda E. Fine, Paul F. Horwood, Philippe Dussart, Stuart D. Blacksell, Mathieu Pruvot, Paul N. Newton, Matthew T. Robinson
المصدر: One Health, Vol 17, Iss , Pp 100618- (2023)
بيانات النشر: Elsevier, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: Wildlife meat, Markets, Laos, Zoonoses, rickettsia, Scrub typhus, Medicine (General), R5-920
الوصف: Wild animal trade for human consumption is a global issue, involving complex interactions between economics, culture, food security and conservation. Whilst being a biodiversity issue, it is also a major public health concern, with recent epidemics and pandemics of zoonotic pathogens linked to interactions with wildlife. At three time points, between March 2017 and June 2018, a longitudinal sero-survey of 150 market vendors from three wet markets in Laos (selling vegetables, domestic animal meat and/or wildlife meat) was conducted to determine if vendors had been differentially exposed to three endemic bacterial pathogens – Orientia tsutsugamushi, Rickettsia typhi, and Leptospira spp. A total of 367 serum samples were tested by IgG enzyme-linked immunosorbent assay (ELISA) and immunofluorescence assay (IFA, for scrub typhus group (STG) and typhus group (TG) only). Among vendors, 32.7% were IgG-positive for at least one pathogen, 13.3% sero-converted during the study. Multi-season occupancy modelling for STG indicated a significantly higher prevalence of STG IgG in vegetable vendors (27.3%) and wildlife vendors (28.4%) than in domestic animal meat vendors (6.9%, p = 0.05), and higher in Phonsavanh market (OR = 9.6, p = 0.03) compared to Lak Sao and Salavan markets. Estimated mean incidence was 57 cases per 10,000 per 7.5-month period. For TG, vendor age had a significant effect on prevalence (OR = 1.04, p = 0.006), estimated mean incidence was 64 cases per 10,000 per season (7.5-month period). Despite individuals selling domestic meat having a higher prevalence of Leptospira infections than those that did not (11.6% versus 4.5%), the difference was not significant. Whilst this study has a number of limitations, including vendors changing what food types they sold and no investigation of exposure outside of markets, the finding that the risk of exposure of vendors to zoonotic pathogens may be associated with types of food sold for human consumption warrants further investigation.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2352-7714
Relation: http://www.sciencedirect.com/science/article/pii/S2352771423001386; https://doaj.org/toc/2352-7714
DOI: 10.1016/j.onehlt.2023.100618
URL الوصول: https://doaj.org/article/d08b523cafc34d11a03b2c479472b77a
رقم الأكسشن: edsdoj.08b523cafc34d11a03b2c479472b77a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23527714
DOI:10.1016/j.onehlt.2023.100618