دورية أكاديمية
Porous Mg–Zn–Ca scaffolds for bone repair: a study on microstructure, mechanical properties and in vitro degradation behavior
| العنوان: | Porous Mg–Zn–Ca scaffolds for bone repair: a study on microstructure, mechanical properties and in vitro degradation behavior |
|---|---|
| المؤلفون: | Lei Huo, Qiang Li, Linlin Jiang, Huiqin Jiang, Jianping Zhao, Kangjian Yang, Qiangsheng Dong, Yi Shao, Chenglin Chu, Feng Xue, Jing Bai |
| المصدر: | Journal of Materials Science: Materials in Medicine, Vol 35, Iss 1, Pp 1-8 (2024) |
| بيانات النشر: | Springer, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Materials of engineering and construction. Mechanics of materials LCC:Medical technology |
| مصطلحات موضوعية: | Bone tissue engineering, Porous Mg-based scaffolds, Mechanical property, Degradability, Materials of engineering and construction. Mechanics of materials, TA401-492, Medical technology, R855-855.5 |
| الوصف: | Abstract Biodegradable porous Mg scaffolds are a promising approach to bone repair. In this work, 3D-spherical porous Mg–1.5Zn–0.2Ca (wt.%) scaffolds were prepared by vacuum infiltration casting technology, and MgF2 and fluorapatite coatings were designed to control the degradation behavior of Mg-based scaffolds. The results showed that the pores in Mg-based scaffolds were composed of the main spherical pores (450–600 μm) and interconnected pores (150–200 μm), and the porosity was up to 74.97%. Mg-based porous scaffolds exhibited sufficient mechanical properties with a compressive yield strength of about 4.04 MPa and elastic modulus of appropriately 0.23 GPa. Besides, both MgF2 coating and fluorapatite coating could effectively improve the corrosion resistance of porous Mg-based scaffolds. In conclusion, this research would provide data support and theoretical guidance for the application of biodegradable porous Mg-based scaffolds in bone tissue engineering. Graphical Abstract |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1573-4838 |
| Relation: | https://doaj.org/toc/1573-4838 |
| DOI: | 10.1007/s10856-023-06754-y |
| URL الوصول: | https://doaj.org/article/08dcac0dd4dd4e3db55e6c57790ba3f0 |
| رقم الأكسشن: | edsdoj.08dcac0dd4dd4e3db55e6c57790ba3f0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 15734838 |
|---|---|
| DOI: | 10.1007/s10856-023-06754-y |