دورية أكاديمية
TOMOGRAPHIC SARCOPENIA PREDICTS ANASTOMOTIC LEAKS AND LONG-TERM SURVIVAL IN GASTRIC CANCER PATIENTS OPERATED WITH CURATIVE INTENT
| العنوان: | TOMOGRAPHIC SARCOPENIA PREDICTS ANASTOMOTIC LEAKS AND LONG-TERM SURVIVAL IN GASTRIC CANCER PATIENTS OPERATED WITH CURATIVE INTENT |
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| المؤلفون: | Manuel Figueroa-Giralt, Francisca Araya, Andrés Torrealba, José Weisz, Enrique Lanzarini, Maher Musleh, Juan Carlos Molina, Owen Korn, Italo Braghetto, Attila Csendes |
| المصدر: | ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 36 (2023) |
| بيانات النشر: | Colégio Brasileiro de Cirurgia Digestiva, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Surgery LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Tomography, Stomach Neoplasms, Fistula, Survival, Sarcopenia, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | ABSTRACT BACKGROUND: The preoperative nutritional state has prognostic postoperative value. Tomographic density and area of psoas muscle are validated tools for assessing nutritional status. There are few reports assessing the utility of staging tomography in gastric cancer patients in this field. AIMS: This study aimed to determine the influence of sarcopenia, measured by a preoperative staging computed tomography scan, on postoperative morbimortality and long-term survival in patients operated on for gastric cancer with curative intent. METHODS: This retrospective study was conducted from 2007 to 2013. The definition of radiological sarcopenia was by measurement of cross-sectional area and density of psoas muscle at the L3 (third lumbar vertebra) level in an axial cut of an abdominopelvic computed tomography scan (in the selection without intravascular contrast media). The software used was OsirixX version 10.0.2, with the tool “propagate segmentation”, and all muscle seen in the image was manually adjusted. RESULTS: We included 70 patients, 77% men, with a mean cross-sectional in L3 of 16.6 cm2 (standard deviation+6.1) and mean density of psoas muscle in L3 of 36.1 mean muscle density (standard deviation+7.1). Advanced cancers were 86, 28.6% had signet-ring cells, 78.6% required a total gastrectomy, postoperative surgical morbidity and mortality were 22.8 and 2.8%, respectively, and overall 5-year long-term survival was 57.1%. In the multivariate analysis, cross-sectional area failed to predict surgical morbidity (p=0.4) and 5-year long-term survival (p=0.34), while density of psoas muscle was able to predict anastomotic fistulas (p=0.009; OR 0.86; 95%CI 0.76–0.96) and 5-year long-term survival (p=0.04; OR 2.9; 95%CI 1.04–8.15). CONCLUSIONS: Tomographic diagnosis of sarcopenia from density of psoas muscle can predict anastomotic fistulas and long-term survival in gastric cancer patients treated with curative intent. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 0102-6720 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202023000100304&tlng=en; https://doaj.org/toc/0102-6720 |
| DOI: | 10.1590/0102-672020230002e1723 |
| URL الوصول: | https://doaj.org/article/0905ba967d5047968e58ed917efb6bcf |
| رقم الأكسشن: | edsdoj.0905ba967d5047968e58ed917efb6bcf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 01026720 |
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| DOI: | 10.1590/0102-672020230002e1723 |