دورية أكاديمية
Clinical implications of low estimated protein intake in patients with heart failure
| العنوان: | Clinical implications of low estimated protein intake in patients with heart failure |
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| المؤلفون: | Koen W. Streng, Hans L. Hillege, Jozine M. terMaaten, Dirk J. vanVeldhuisen, Kenneth Dickstein, Leong L. Ng, Nilesh J. Samani, Marco Metra, Piotr Ponikowski, John G. Cleland, Stefan D. Anker, Simon P.R. Romaine, Kevin Damman, Peter van derMeer, Chim C. Lang, Adriaan A. Voors |
| المصدر: | Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1762-1770 (2022) |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the musculoskeletal system LCC:Human anatomy |
| مصطلحات موضوعية: | Heart failure, Obesity, Body mass index, Protein, Mortality, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695 |
| الوصف: | Abstract Background A higher protein intake has been associated with a higher muscle mass and lower mortality rates in the general population, but data about protein intake and survival in patients with heart failure (HF) are lacking. Methods We studied the prevalence, predictors, and clinical outcome of estimated protein intake in 2516 patients from the BIOlogy Study to TAilored Treatment in Chronic Heart Failure (BIOSTAT‐CHF) index cohort. Protein intake was calculated in spot urine samples using a validated formula [13.9 + 0.907 * body mass index (BMI) (kg/m2) + 0.0305 * urinary urea nitrogen level (mg/dL)]. Association with mortality was assessed using multivariable Cox regression models. All findings were validated in an independent cohort. Results We included 2282 HF patients (mean age 68 ± 12 years and 27% female). Lower estimated protein intake in HF patients was associated with a lower BMI, but with more signs of congestion. Mortality rate in the lowest quartile was 32%, compared with 18% in the highest quartile (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2190-6009 2190-5991 |
| Relation: | https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009 |
| DOI: | 10.1002/jcsm.12973 |
| URL الوصول: | https://doaj.org/article/09abab01211642089de26c745d0136e0 |
| رقم الأكسشن: | edsdoj.09abab01211642089de26c745d0136e0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21906009 21905991 |
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| DOI: | 10.1002/jcsm.12973 |