دورية أكاديمية
Inflammatory bowel disease in the elderly: A focus on disease characteristics and treatment patterns
| العنوان: | Inflammatory bowel disease in the elderly: A focus on disease characteristics and treatment patterns |
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| المؤلفون: | Mahmoud H Mosli, Maha K Alghamdi, Omar A Bokhary, Maria A Alzahrani, Siba Z Takieddin, Tala A Galai, Majid A Alsahafi, Omar I Saadah |
| المصدر: | The Saudi Journal of Gastroenterology, Vol 29, Iss 4, Pp 212-218 (2023) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | crohn's disease, elderly, inflammatory bowel disease, montréal classification, ulcerative colitis, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background: As the population ages, the number of elderly inflammatory bowel disease (IBD) patients is expected to increase. The clinical features and therapeutic options for young and old patients may differ, as elderly IBD patients are likely to have different comorbidities and disease characteristics. The goal of this study was to examine the clinical aspects and therapeutic choices for elderly Saudi IBD patients. Methods: We conducted a retrospective study aimed at describing the demographic, clinical, and management characteristics of IBD in elderly patients (≥60 years) who followed up at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. The data was extracted from the KAUH inflammatory bowel disease information system (IBDIS) registry. The primary outcome was to describe disease characteristics in accordance with the Montréal classification and the secondary outcomes were to describe treatment patterns and identify significant clinical associations. Results: Our data were collected from 76 patients who fulfilled the study inclusion criteria. Females outnumbered males (53.9% vs 46.1%) and the mean age was 51.5 ± 9.7 years. Essential hypertension (26.3%) was the most common comorbidity followed by diabetes mellitus (23.6%), and malignant neoplasms (9.21%). More than half of the patients with Crohn's disease (CD) had disease onset after forty years of age. The most common form of disease distribution was ileocolonic disease (64.7%). Less than 17% of patients had a penetrating disease phenotype. About 88 percent of patients with UC presented >40 years of age. Approximately, half of the cohort had left-sided ulcerative colitis (UC) (48%), followed by pancolitis (40%). The most prescribed medication class for IBD was 5-aminosalicylic acid (5-ASA) derivatives (56.58%) followed by corticosteroids and immunosuppressive drugs. Conclusions: In Saudi Arabia, age-specific concerns including comorbidities and polypharmacy remain the major challenges in the management of elderly IBD patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1319-3767 1998-4049 |
| Relation: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2023;volume=29;issue=4;spage=212;epage=218;aulast=Mosli; https://doaj.org/toc/1319-3767; https://doaj.org/toc/1998-4049 |
| DOI: | 10.4103/sjg.sjg_503_22 |
| URL الوصول: | https://doaj.org/article/e09bd4a8df494d4e92a861616c93a2a8 |
| رقم الأكسشن: | edsdoj.09bd4a8df494d4e92a861616c93a2a8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13193767 19984049 |
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| DOI: | 10.4103/sjg.sjg_503_22 |