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The prognostic impact of bone metastasis in patients with metastatic urothelial carcinoma treated with first-line platinum-based chemotherapy

التفاصيل البيبلوغرافية
العنوان: The prognostic impact of bone metastasis in patients with metastatic urothelial carcinoma treated with first-line platinum-based chemotherapy
المؤلفون: Husam A. Alqaisi, Carlos Stecca, Zachary W. Veitch, Jamila Riromar, Jeenan Kaiser, Nazanin Fallah-Rad, Di Maria Jiang, Scott North, Sunil Samnani, Nimira Alimohamed, Srikala S. Sridhar
المصدر: Therapeutic Advances in Medical Oncology, Vol 14 (2022)
بيانات النشر: SAGE Publishing, 2022.
سنة النشر: 2022
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Background: In metastatic urothelial cancer (mUC), bone metastasis (BM) are associated with significant morbidity and mortality, yet their role as an independent prognostic variable remains unclear. We aimed to determine the impact of BM on overall survival (OS) in patients with mUC treated with first-line platinum-based chemotherapy (PBC). Methods: mUC patients receiving PBC at the Princess Margaret Cancer Center, Tom Baker Cancer Center, or Cross Cancer Institute from January 2005 to January 2018 were identified retrospectively using central pharmacy database records. Patient disease, treatment, and response characteristics were collected. Progression-free survival (PFS) and OS were estimated using the Kaplan–Meier method. Variables reaching significance ( p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1758-8359
17588359
Relation: https://doaj.org/toc/1758-8359
DOI: 10.1177/17588359221094879
URL الوصول: https://doaj.org/article/09c2af7facc04086bb1a915a240fde56
رقم الأكسشن: edsdoj.09c2af7facc04086bb1a915a240fde56
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17588359
DOI:10.1177/17588359221094879