دورية أكاديمية
The prognostic impact of bone metastasis in patients with metastatic urothelial carcinoma treated with first-line platinum-based chemotherapy
العنوان: | The prognostic impact of bone metastasis in patients with metastatic urothelial carcinoma treated with first-line platinum-based chemotherapy |
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المؤلفون: | Husam A. Alqaisi, Carlos Stecca, Zachary W. Veitch, Jamila Riromar, Jeenan Kaiser, Nazanin Fallah-Rad, Di Maria Jiang, Scott North, Sunil Samnani, Nimira Alimohamed, Srikala S. Sridhar |
المصدر: | Therapeutic Advances in Medical Oncology, Vol 14 (2022) |
بيانات النشر: | SAGE Publishing, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Background: In metastatic urothelial cancer (mUC), bone metastasis (BM) are associated with significant morbidity and mortality, yet their role as an independent prognostic variable remains unclear. We aimed to determine the impact of BM on overall survival (OS) in patients with mUC treated with first-line platinum-based chemotherapy (PBC). Methods: mUC patients receiving PBC at the Princess Margaret Cancer Center, Tom Baker Cancer Center, or Cross Cancer Institute from January 2005 to January 2018 were identified retrospectively using central pharmacy database records. Patient disease, treatment, and response characteristics were collected. Progression-free survival (PFS) and OS were estimated using the Kaplan–Meier method. Variables reaching significance ( p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1758-8359 17588359 |
Relation: | https://doaj.org/toc/1758-8359 |
DOI: | 10.1177/17588359221094879 |
URL الوصول: | https://doaj.org/article/09c2af7facc04086bb1a915a240fde56 |
رقم الأكسشن: | edsdoj.09c2af7facc04086bb1a915a240fde56 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17588359 |
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DOI: | 10.1177/17588359221094879 |