Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

التفاصيل البيبلوغرافية
العنوان:	Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth
المؤلفون:	Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Sarah Birke, Priyanka Murawala, Ezzaldin Ahmed Alfar, Kei Murata, Anne Eugster, Naoki Tsuji, Edward R. Morrissey, Michael Brand, Nikolay Ninov
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Βeta-cells have recently been shown to be heterogeneous with regard to morphology and function. Here, the authors show that β-cells in zebrafish switch from proliferative to functional states with increasing time since β-cell birth, leading to functional and proliferative heterogeneity.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-017-00461-3
URL الوصول:	https://doaj.org/article/09d63bb2e4484ac98df9ddecef7e0e11
رقم الأكسشن:	edsdoj.09d63bb2e4484ac98df9ddecef7e0e11
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-017-00461-3