دورية أكاديمية
Impact of surgical approach on 90-day mortality after lung resection for nonsmall cell lung cancer in high-risk operable patients
| العنوان: | Impact of surgical approach on 90-day mortality after lung resection for nonsmall cell lung cancer in high-risk operable patients |
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| المؤلفون: | Harry Etienne, Pierre-Benoît Pagès, Jules Iquille, Pierre Emmanuel Falcoz, Laurent Brouchet, Jean-Philippe Berthet, Françoise Le Pimpec Barthes, Jacques Jougon, Marc Filaire, Jean-Marc Baste, Valentine Anne, Stéphane Renaud, Thomas D'Annoville, Jean Pierre Meunier, Christophe Jayle, Christian Dromer, Agathe Seguin-Givelet, Antoine Legras, Philippe Rinieri, Sophie Jaillard-Thery, Vincent Margot, Pascal-Alexandre Thomas, Marcel Dahan, Pierre Mordant |
| المصدر: | ERJ Open Research, Vol 10, Iss 1 (2024) |
| بيانات النشر: | European Respiratory Society, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Medicine |
| الوصف: | Introduction Non-small cell lung cancer (NSCLC) is often associated with compromised lung function. Real-world data on the impact of surgical approach in NSCLC patients with compromised lung function are still lacking. The objective of this study is to assess the potential impact of minimally invasive surgery (MIS) on 90-day post-operative mortality after anatomic lung resection in high-risk operable NSCLC patients. Methods We conducted a retrospective multicentre study including all patients who underwent anatomic lung resection between January 2010 and October 2021 and registered in the Epithor database. High-risk patients were defined as those with a forced expiratory volume in 1 s (FEV1) or diffusing capacity of the lung for carbon monoxide (DLCO) value below 50%. Co-primary end-points were the impact of risk status on 90-day mortality and the impact of MIS on 90-day mortality in high-risk patients. Results Of the 46 909 patients who met the inclusion criteria, 42 214 patients (90%) with both preoperative FEV1 and DLCO above 50% were included in the low-risk group, and 4695 patients (10%) with preoperative FEV1 and/or preoperative DLCO below 50% were included in the high-risk group. The 90-day mortality rate was significantly higher in the high-risk group compared to the low-risk group (280 (5.96%) versus 1301 (3.18%); p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2312-0541 23120541 |
| Relation: | http://openres.ersjournals.com/content/10/1/00653-2023.full; https://doaj.org/toc/2312-0541 |
| DOI: | 10.1183/23120541.00653-2023 |
| URL الوصول: | https://doaj.org/article/09fbb8a9ab6e4785a088d1be5b101ff6 |
| رقم الأكسشن: | edsdoj.09fbb8a9ab6e4785a088d1be5b101ff6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23120541 |
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| DOI: | 10.1183/23120541.00653-2023 |