دورية أكاديمية
Evolution and Spread of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea, 2022–2023
| العنوان: | Evolution and Spread of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea, 2022–2023 |
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| المؤلفون: | Ye-Ram Seo, Andrew Y. Cho, Young-Jae Si, Song-I Lee, Dong-Ju Kim, Hyesung Jeong, Jung-Hoon Kwon, Chang-Seon Song, Dong-Hun Lee |
| المصدر: | Emerging Infectious Diseases, Vol 30, Iss 2, Pp 299-309 (2024) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | influenza, highly pathogenic avian influenza virus, H5N1, clade 2.3.4.4b, wild bird, South Korea, Medicine, Infectious and parasitic diseases, RC109-216 |
| الوصف: | During October 2022–March 2023, highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b virus caused outbreaks in South Korea, including 174 cases in wild birds. To understand the origin and role of wild birds in the evolution and spread of HPAI viruses, we sequenced 113 HPAI isolates from wild birds and performed phylogenetic analysis. We identified 16 different genotypes, indicating extensive genetic reassortment with viruses in wild birds. Phylodynamic analysis showed that the viruses were most likely introduced to the southern Gyeonggi-do/northern Chungcheongnam-do area through whooper swans (Cygnus cygnus) and spread southward. Cross-species transmission occurred between various wild bird species, including waterfowl and raptors, resulting in the persistence of HPAI in wild bird populations and further geographic spread as these birds migrated throughout South Korea. Enhanced genomic surveillance was an integral part of the HPAI outbreak response, aiding in timely understanding of the origin, evolution, and spread of the virus. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/30/2/23-1274_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid3002.231274 |
| URL الوصول: | https://doaj.org/article/0aa51e0ca305439bb5de1dc529f0008a |
| رقم الأكسشن: | edsdoj.0aa51e0ca305439bb5de1dc529f0008a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10806040 10806059 |
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| DOI: | 10.3201/eid3002.231274 |