دورية أكاديمية
Cardiorenal relationships in the focus of risks of atrial fibrillation in patients after acute ST-elevated myocardial infarction (observational program FAKEL)
| العنوان: | Cardiorenal relationships in the focus of risks of atrial fibrillation in patients after acute ST-elevated myocardial infarction (observational program FAKEL) |
|---|---|
| المؤلفون: | I. A. Zolotovskaya, I. L. Davydkin, D. V. Duplyakov, V. A. Kokorin |
| المصدر: | Рациональная фармакотерапия в кардиологии, Vol 15, Iss 2, Pp 159-165 (2019) |
| بيانات النشر: | Столичная издательская компания, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Therapeutics. Pharmacology LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | myocardial infarction, atrial fibrillation, cardioembolic stroke, prevention, mortality, nt-probnp, galectin-3, cystatin c, von willebrand factor, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Aim. To study markers of renal dysfunction in relation to the likelihood of atrial fibrillation (AF) in patients after ST-segment elevated myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).Material and methods. The study was conducted with the inclusion of 1 52 patients discharged for outpatient monitoring after STEMI. There were 4 visits: V1 - inclusion visit, V2 - in 12 months, V3 - in 18 months, V4- in 24 months with determination of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP), cystatin C, erythropoietin, galectin-3, von Willebrand factor (fW), left ventricular ejection fraction. Endpoint: new cases of AF, cardioembolic stroke, deaths.Results. After 24 months 35 patients (23.0%) were diagnosed with AF, 6 of them (3.9%) - developed cardioembolic stroke. The multivariate model of risk factors for AF included indicators: cystatin C (odds ratio [OR] 1.31; 95% confidence interval [95%CI] 1.03-1.67), NT-ProBNP (OR 1.11; 95%CI 1.03-1.19), galectin-3 (OR 0.71; 95%CI 0.55-0.91), fV (OR 0.71; 95%CI 0.55-0.91).Conclusion. The prognostic significance of cystatin C in relation to the risk of AF was established, which should be considered when assessing the prognosis in patients after STEMI. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Russian |
| تدمد: | 1819-6446 2225-3653 |
| Relation: | https://www.rpcardio.online/jour/article/view/1908; https://doaj.org/toc/1819-6446; https://doaj.org/toc/2225-3653 |
| DOI: | 10.20996/1819-6446-2019-15-2-159-165 |
| URL الوصول: | https://doaj.org/article/0ab58e7d7af74f8fad0423e02765697f |
| رقم الأكسشن: | edsdoj.0ab58e7d7af74f8fad0423e02765697f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18196446 22253653 |
|---|---|
| DOI: | 10.20996/1819-6446-2019-15-2-159-165 |