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Association between urinary manganese and pulmonary function in young adults: A cross-sectional design with a longitudinal cohort validation

التفاصيل البيبلوغرافية
العنوان: Association between urinary manganese and pulmonary function in young adults: A cross-sectional design with a longitudinal cohort validation
المؤلفون: Chin-Chung Shu, Jia-Kun Chen, Po-Chin Huang, Jing-Shiang Hwang, Ta-Chen Su
المصدر: Ecotoxicology and Environmental Safety, Vol 227, Iss , Pp 112937- (2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
المجموعة: LCC:Environmental pollution
LCC:Environmental sciences
مصطلحات موضوعية: Cohort study, Forced vital capacity, Forced expiratory volume, Urinary manganese, Copper, Iron, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350
الوصف: Background: The impact of heavy metals on pulmonary function among young adults has been scarcely studied, especially by a longitudinal cohort study. Methods: We prospectively enrolled 974 young adults (aged 20–45 years) during 2017–2019 and measured pulmonary function and urinary heavy metals, including manganese, copper, chromium, iron, nickel, zinc, cadmium, and lead. Among them, 461 participants had examination of the same urinary heavy metals during 2006–2008, which could be used as a cohort for long-term effect of urinary metals on pulmonary function. Results: In the 974 enrolled participants, urinary heavy metals were within normal range. The urinary manganese level was the only significant factor for the observed/predicted ratios of forced vital capacity (FVC %)(β coefficient: −1.217, p = 0.030), forced expiratory volume in one second (FEV1%)(β: −1.664, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0147-6513
Relation: http://www.sciencedirect.com/science/article/pii/S0147651321010496; https://doaj.org/toc/0147-6513
DOI: 10.1016/j.ecoenv.2021.112937
URL الوصول: https://doaj.org/article/c0ae2c40e30a473c89756e4797a72fde
رقم الأكسشن: edsdoj.0ae2c40e30a473c89756e4797a72fde
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:01476513
DOI:10.1016/j.ecoenv.2021.112937