دورية أكاديمية
Choriocarcinoma in Northwestern Nigeria: A histopathological review
| العنوان: | Choriocarcinoma in Northwestern Nigeria: A histopathological review |
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| المؤلفون: | A A Mayun, A H Rafindadi, M S Shehu |
| المصدر: | Nigerian Postgraduate Medical Journal, Vol 19, Iss 4, Pp 215-218 (2012) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | choriocarcinoma, histopathological appearance, north-western nigeria, Medicine |
| الوصف: | Aims and Objectives: Gestational choriocarcinoma is a malignant form of gestational trophoblastic disease with a highly aggressive biologic behavior and responds well to chemotherapy. The objective of this study is to analyse the various histological features of this neoplasm as seen in Ahmadu Bello University Teaching hospital, ( ABUTH ) Zaria, determine its incidence, and compare with other studies. Materials and methods: The bench registers were used to retrieve the request forms, slides, and tissue blocks. The slides were all stained with standard haematoxylin and Eosin. The histological criteria published by Gehrig and van Lee was used to diagnose the tumours and grading of the cases from grade I to III. Results: Forty three cases were studied and these formed 4.9% of all products of conception and 37.7% of all gestational trophoblastic diseases. The peak age of incidence was in the third and fourth decades of life with vaginal bleeding as the leading mode of presentation. Extensive histopathological analysis and grading revealed haemorrhage, necrosis diamorphic appearance and pleomorphism as the most frequent features. Conclusion: Gestational choriocarcinoma is a common problem in Zaria, North- Western Nigeria with an incidence of 1 in 1039 deliveries. Haemorrhage, necrosis, diamorphic appearance and pleomorphism were the most frequent histological features. Health education and early detection are of paramount importance in reducing morbidity and mortality. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1117-1936 2468-6875 |
| Relation: | http://www.npmj.org/article.asp?issn=1117-1936;year=2012;volume=19;issue=4;spage=215;epage=218;aulast=Mayun; https://doaj.org/toc/1117-1936; https://doaj.org/toc/2468-6875 |
| URL الوصول: | https://doaj.org/article/0be3111c6bd64669ad4855bdac84aab5 |
| رقم الأكسشن: | edsdoj.0be3111c6bd64669ad4855bdac84aab5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 11171936 24686875 |
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