دورية أكاديمية
Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers
| العنوان: | Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers |
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| المؤلفون: | Robert G. Hahn |
| المصدر: | BMC Nutrition, Vol 9, Iss 1, Pp 1-11 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Food processing and manufacture LCC:Medicine (General) |
| مصطلحات موضوعية: | Biomarkers, Creatinine, Hydration status, Fluid retention, Osmolality, Urine analysis, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456, Medicine (General), R5-920 |
| الوصف: | Abstract Background The hydration status can be indicated by biomarkers in the urine. However, the sensitivity and specificity of single measurements of biomarkers in morning urine and spot urine samples to quantify previous and current daily water ingestion is unclear. Methods The water content of food and liquid consumed by 20 volunteers (mean age 42 years) was calculated daily for two weeks. The volunteers increased their consumption of water by approximately 30% during the second week. They measured their excreted urine volume and sampled the morning urine and 24-h collections of urine for analysis of osmolality and creatinine during the first four days of both weeks (N = 157). The same biomarkers of hydration were measured in spot samples taken at every voiding on the other days (N = 762). Receiver operating characteristic (ROC) curves were used to study the ability of pre-specified ranges of biomarkers to quantify the water intake. Results The biomarkers in the morning urine obtained during normal fluid intake quantified the water consumption with an average area under the ROC curve (AUC) of 0.72 for osmolality and 0.66 for creatinine. Spot urine yielded an AUC of 0.74 for osmolality and 0.70 for creatinine. The AUCs obtained for days of increased fluid intake were approximately 10% lower. Large intakes (3–4 L daily) were identified with a sensitivity of 50–80% and low intakes ( |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2055-0928 |
| Relation: | https://doaj.org/toc/2055-0928 |
| DOI: | 10.1186/s40795-022-00660-2 |
| URL الوصول: | https://doaj.org/article/0c87b857b5ec44fb970a5168c2a240bc |
| رقم الأكسشن: | edsdoj.0c87b857b5ec44fb970a5168c2a240bc |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20550928 |
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| DOI: | 10.1186/s40795-022-00660-2 |