دورية أكاديمية
أعرض في EDS

Outcome measures and treatment effectiveness in late onset myasthenia gravis

التفاصيل البيبلوغرافية
العنوان: Outcome measures and treatment effectiveness in late onset myasthenia gravis
المؤلفون: Francesca Pasqualin, Silvia V. Guidoni, Mario Ermani, Elena Pegoraro, Domenico M. Bonifati
المصدر: Neurological Research and Practice, Vol 2, Iss 1, Pp 1-7 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
LCC:Neurology. Diseases of the nervous system
مصطلحات موضوعية: MGFA-PIS, MGSTI, Myasthenia gravis, Characterization, Outcome, LOMG, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
الوصف: Abstract Background Recently different subtypes of myasthenia gravis (MG) have been described. They differ for clinical features and pathogenesis but the prognosis and response to treatment is less clear. The aim of the study was to evaluate outcome and treatment effectiveness including side effects in late onset MG (LOMG) compared with early onset MG (EOMG). Methods We analysed retrospectively 208 MG patients. Clinical features were recorded as well as treatment and side effects. Outcome at the last follow-up was evaluated with MGSTI and MGPIS scales. Results The 208 patients included were classified as follow: 36 ocular MG, 40 EOMG, 72 LOMG, 25 thymoma-associated, 14 anti-MuSK and 21 double seronegative. Similar positive outcome was achieved in either early and late onset subgroup. We found pharmacological remission and minimal manifestations at the MGFA-PIS in the 95% and 94,4% of EOMG and LOMG respectively but in LOMG a lower dose of immunosuppressors (MGSTI
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2524-3489
Relation: http://link.springer.com/article/10.1186/s42466-020-00091-z; https://doaj.org/toc/2524-3489
DOI: 10.1186/s42466-020-00091-z
URL الوصول: https://doaj.org/article/0d9f30e31b254f6b880b67948e20a039
رقم الأكسشن: edsdoj.0d9f30e31b254f6b880b67948e20a039
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:25243489
DOI:10.1186/s42466-020-00091-z