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Insight study on synthesis and antibacterial mechanism of silver nanoparticles prepared from indigenous plant source of Jharkhand

التفاصيل البيبلوغرافية
العنوان: Insight study on synthesis and antibacterial mechanism of silver nanoparticles prepared from indigenous plant source of Jharkhand
المؤلفون: Koel Mukherjee, Namrata Bhagat, Madhubala Kumari, Arnab Roy Choudhury, Biplab Sarkar, Barnali Dasgupta Ghosh
المصدر: Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
بيانات النشر: Elsevier, 2023.
سنة النشر: 2023
المجموعة: LCC:Biotechnology
LCC:Genetics
مصطلحات موضوعية: Ag-NPs, Indigenous plant, Litsea glutinosa, Polygonum plebeium, Vangueria spinosus, Biotechnology, TP248.13-248.65, Genetics, QH426-470
الوصف: Abstract Background The Ag-NPs by green synthesis has a notable interest because of their eco-friendliness, economic views, feasibility, and applications in a wide range. Herein, native plants of Jharkhand (Polygonum plebeium, Litsea glutinosa, and Vangueria spinosus) were selected for the current work of Ag-NP synthesis and further antibacterial activity. Green synthesis was performed for Ag-NPs using Silver nitrate solution as precursor and the dried leaf extract performs as a reductant and stabilizer here. Result Visually Ag-NP formation was observed along with a colour change and confirmed by UV-visible spectrophotometry on which an absorbance peak occurs at around 400–450nm. Further characterization was done on DLS, FTIR, FESEM, and XRD. Size around 45–86 nm of synthesized Ag-NPs was predicted through DLS. The synthesized Ag-NPs exhibited significant antibacterial activity against Bacillus subtilis (Gram-positive bacteria) and Salmonella typhi (Gram-negative bacteria). The finest antibacterial activity was disclosed by the Ag-NPs synthesized by Polygonum plebeium extract. The diameter of the zone of inhibition in the bacterial plate measured was 0–1.8 mm in Bacillus and 0–2.2 mm in Salmonella typhi. Protein-Protein interaction study was performed to study the effect of Ag-NPs towards different antioxidant enzyme system of bacterial cell. Conclusion Present work suggest the Ag-NPs synthesized from P. plebeium were more stable for long term and might have prolonged antibacterial activity. In the future, these Ag-NPs can be applied in various fields like antimicrobial research, wound healing, drug delivery, bio-sensing, tumour/cancer cell treatment, and detector (detect solar energy). Graphical abstract Schematic representation of Ag-NPs green synthesis, characterization, antibacterial activity and at the end, in silico study to analyse the mechanism of antibacterial activity
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2090-5920
Relation: https://doaj.org/toc/2090-5920
DOI: 10.1186/s43141-023-00463-3
URL الوصول: https://doaj.org/article/a0de19e6f389440baefbe4947fbe9d1f
رقم الأكسشن: edsdoj.0de19e6f389440baefbe4947fbe9d1f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20905920
DOI:10.1186/s43141-023-00463-3