دورية أكاديمية

7,8,15,16-tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity

التفاصيل البيبلوغرافية
العنوان: 7,8,15,16-tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity
المؤلفون: BOGDAN SOLAJA, WILBUR K. MILHOUS, DEJAN OPSENICA, NATASA TERZIC, IGOR OPSENICA
المصدر: Journal of the Serbian Chemical Society, Vol 69, Iss 11, Pp 919-922 (2004)
بيانات النشر: Serbian Chemical Society, 2004.
سنة النشر: 2004
المجموعة: LCC:Chemistry
مصطلحات موضوعية: mixed tetraoxane, malaria, Plasmodium falciparum, gem-dihydroperoxide, Chemistry, QD1-999
الوصف: Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 strains, with N-(2-dimethylamino)ethyl-7,8,15,16-tetraoxa-dispiro[5.2.5.2] hexadecane-3-carboxamide being as active as artemisinin.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0352-5139
Relation: http://www.shd.org.yu/HtDocs/SHD/Vol69/No11/V69-No11-11.pdf; https://doaj.org/toc/0352-5139
URL الوصول: https://doaj.org/article/0df4ef50252c44d293cdf1ec13ca5903
رقم الأكسشن: edsdoj.0df4ef50252c44d293cdf1ec13ca5903
قاعدة البيانات: Directory of Open Access Journals