دورية أكاديمية

Literature review in the treatment of calciphylaxis:A case with uncontrolled and severe secondary hyperparathyroidism

التفاصيل البيبلوغرافية
العنوان: Literature review in the treatment of calciphylaxis:A case with uncontrolled and severe secondary hyperparathyroidism
المؤلفون: Ali Abbas Ozdemir, Murat Altay, Aslan Celebi, Osman Mavis
المصدر: Caspian Journal of Internal Medicine, Vol 7, Iss 1, Pp 57-60 (2016)
بيانات النشر: Babol University of Medical Sciences, 2016.
سنة النشر: 2016
المجموعة: LCC:Internal medicine
مصطلحات موضوعية: Kidney Failure, Hyperparathyroidism, Calciphylaxis, Internal medicine, RC31-1245
الوصف: Background: Calciphylaxis is a serious disorder often observed in dialysis patients and less frequently in chronic renal failure patients with secondary hyperparathyroidism. Mortality rate increases following the development of calciphylaxis, immediate application of parathyroidectomy along with other treatment options may be lifesaving. Case Presentation: A 44-year-old male patient had been on regular hemodialysis three times per week, with 4-hour sessions since December 2003. The etiology of his renal failure was unknown and the patient had no systemic disease when hemodialysis was started, painful, erythematous skin lesions were detected over and around the external malleolus of the right foot. In the next two months, erythematous skin lesions gained a necrosed character and spread into the malleolar and posterior tibial region and back of the ankle in both extremities. The patient showed no clinical signs of recovery and despite anti-biotherapy, debridement and protective measures, the skin lesions got infected and presented as intolerable, painful wounds. The patient was diagnosed with calcific uremic arteriolopathy (CUA) and hospitalized for parathyroidectomy. All parathyroid glands were removed after having checked quick PTH intraoperatively. A small amount of parathyroid tissue was intramuscularly auto-implanted into the right forearm .Skin lesions showed fast improvement in further follow-ups. Three months after parathyroidectomy, iPTH value was measured as 1197 pg/ml. After 6 months of medical treatment, iPTH was found as 970 ng/L and we decided to remove the implanted parathyroid tissue from the right forearm. Conclusion: In this article, we present a case of calciphylaxis accompanied by severe secondary hyperparathyroidism.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2008-6164
2008-6172
Relation: http://caspjim.com/browse.php?a_code=A-10-341-1&slc_lang=en&sid=1; https://doaj.org/toc/2008-6164; https://doaj.org/toc/2008-6172
URL الوصول: https://doaj.org/article/0df5149610284d8aa31f3ee934b7e512
رقم الأكسشن: edsdoj.0df5149610284d8aa31f3ee934b7e512
قاعدة البيانات: Directory of Open Access Journals