دورية أكاديمية
Synthesis, Anti-inflammatory and Antioxidant Activities of Novel 3H-Thiazolo[4,5-b]pyridines
| العنوان: | Synthesis, Anti-inflammatory and Antioxidant Activities of Novel 3H-Thiazolo[4,5-b]pyridines |
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| المؤلفون: | Taras I. Chaban, Volodymyr V. Ogurtsov, Vasyl S. Matiychuk, Ihor G. Chaban, Inna L. Demchuk, Ihor A. Nektegayev |
| المصدر: | Acta Chimica Slovenica, Vol 66, Iss 1, Pp 103-111 (2019) |
| بيانات النشر: | Slovenian Chemical Society, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | thiazolo[4,5-b]pyridines, synthesis, anti-inflammatory activity, antioxidant activity, Chemistry, QD1-999 |
| الوصف: | 5-Hydroxy-7-methyl-3H-thiazolo[4,5-b]pyridin-2-one was obtained by the reaction of 4-iminothiazolidin-2-one with acetoacetic ester. Further structural modifications include the introduction of diversity at the C5 and C6 positions. The anti-inflammatory action of novel thiazolo[4,5-b]pyridine-2-one derivatives was evaluated in vivo employing the carrageenan-induced rat paw edema method. The antioxidant activity of the synthesized compounds was evaluated in vitro by the method of scavenging effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1318-0207 1580-3155 |
| Relation: | https://journals.matheo.si/index.php/ACSi/article/view/4570; https://doaj.org/toc/1318-0207; https://doaj.org/toc/1580-3155 |
| DOI: | 10.17344/acsi.2018.4570 |
| URL الوصول: | https://doaj.org/article/0e1d5494b20e4716a19983c7f8924ede |
| رقم الأكسشن: | edsdoj.0e1d5494b20e4716a19983c7f8924ede |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13180207 15803155 |
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| DOI: | 10.17344/acsi.2018.4570 |