دورية أكاديمية

The Use of Interactive Visualizations for Tracking Haplotypic Inheritance in Livestock

التفاصيل البيبلوغرافية
العنوان: The Use of Interactive Visualizations for Tracking Haplotypic Inheritance in Livestock
المؤلفون: Alana Selli, Stephen P. Miller, Ricardo V. Ventura
المصدر: Ruminants, Vol 4, Iss 1, Pp 90-111 (2024)
بيانات النشر: MDPI AG, 2024.
سنة النشر: 2024
المجموعة: LCC:Nutrition. Foods and food supply
مصطلحات موضوعية: beef cattle simulation, genomic selection, genomic visualization, haplotype transmission, livestock genetics, open-source tools, Nutrition. Foods and food supply, TX341-641
الوصف: Our objective was to harness the power of interactive visualizations by utilizing open-source tools to develop an efficient strategy for visualizing Single Nucleotide Polymorphism data within a livestock population, focusing on tracking the transmission of haplotypes. To achieve this, we simulated a realistic beef cattle population in order to obtain phased haplotypes and generate the necessary inputs for creating our visualizations. The visualization tool was built using Python and the Plotly library, which enables interactivity. We set out to explore three scenarios: trio comparison, visualization of grandparents, and half-sibling evaluation. These scenarios enabled us to trace the inheritance of genetic segments, identify crossover events, and uncover common regions within related and unrelated animals. The potential applications of this approach are significant, particularly for improving genomic selection in smaller breeding programs and farms, and it provides valuable insights for guiding more in-depth genomic region analysis. Beyond its practical applications, we believe this strategy can be a valuable educational tool, helping educators clarify complex concepts like Mendelian sampling and haplotypic diversity. Furthermore, we hope it will encourage livestock producers to adopt advanced technologies like genotyping and genomic selection, thereby contributing to the advancement of livestock genetics.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2673-933X
Relation: https://www.mdpi.com/2673-933X/4/1/6; https://doaj.org/toc/2673-933X
DOI: 10.3390/ruminants4010006
URL الوصول: https://doaj.org/article/c0eb3271462543e9817c6e7c57e17f03
رقم الأكسشن: edsdoj.0eb3271462543e9817c6e7c57e17f03
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2673933X
DOI:10.3390/ruminants4010006