دورية أكاديمية
An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases
| العنوان: | An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases |
|---|---|
| المؤلفون: | Yanyun Li, Ziyu Ye, Weiqin Yang, Qunzhou Zhang, Jincheng Zeng |
| المصدر: | Stem Cells International, Vol 2021 (2021) |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Internal medicine |
| مصطلحات موضوعية: | Internal medicine, RC31-1245 |
| الوصف: | Mesenchymal stem or stromal cells (MSCs) are nonhematopoietic postnatal stem cells with self-renewal, multipotent differentiation, and potent immunomodulatory and anti-inflammatory capabilities, thus playing an important role in tissue repair and regeneration. Numerous clinical and preclinical studies have demonstrated the potential application of MSCs in the treatment of tissue inflammation and immune diseases, including inflammatory skin diseases. Therefore, understanding the biological and immunological characteristics of MSCs is important to standardize and optimize MSC-based regenerative therapy. In this review, we highlight the mechanisms underlying MSC-mediated immunomodulation and tissue repair/regeneration and present the latest development of MSC-based clinical trials on cutaneous diseases. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1687-966X 1687-9678 |
| Relation: | https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678 |
| DOI: | 10.1155/2021/8834590 |
| URL الوصول: | https://doaj.org/article/de0f1cabda99483db08139554dfbac41 |
| رقم الأكسشن: | edsdoj.0f1cabda99483db08139554dfbac41 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1687966X 16879678 |
|---|---|
| DOI: | 10.1155/2021/8834590 |