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Long-term immune responses in patients with confirmed novel coronavirus disease-2019: a 9-month prospective cohort study in Shanghai, China

التفاصيل البيبلوغرافية
العنوان: Long-term immune responses in patients with confirmed novel coronavirus disease-2019: a 9-month prospective cohort study in Shanghai, China
المؤلفون: Xiaohuan Gong, Peng Cui, Huanyu Wu, Hao Pan, Zheng Teng, Fang Yuan, Shenghua Mao, Dechuan Kong, Ruobing Han, Xue Zhao, Yaxu Zheng, Wenjia Xiao, Yiyi Zhu, Qiwen Fang, Sheng Lin, Bihong Jin, Ruilin Chu, Chenyan Jiang, Xiao Yu, Qi Qiu, Yihan Lu, Weibing Wang, Chen Fu, Xiaodong Sun
المصدر: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-14 (2022)
بيانات النشر: BMC, 2022.
سنة النشر: 2022
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Covid-19, SARS-CoV-2, Cohort study, Antibodies, Immunity, Infectious and parasitic diseases, RC109-216
الوصف: Abstract Background The duration of antibodies against SARS-CoV-2 in Covid-19 patients remains uncertain. Longitudinal serological studies are needed to prevent disease and transmission of the virus. Methods In 2020, 414 blood samples were tested, obtained from 157 confirmed Covid-19 patients, in a prospective cohort study in Shanghai. Results The seropositive rate of IgM peaked at 40.5% (17/42) within 1 month after illness onset and then declined. The seropositive rate of IgG was 90.6% (58/64) after 2 months, remained above 85% from 2 to 9 months and was 90.9% (40/44) after 9 months. Generalized estimating equations models suggested that IgM (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2334
Relation: https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-022-07173-0
URL الوصول: https://doaj.org/article/d0f6c708f580494dbe96e4637823ed9b
رقم الأكسشن: edsdoj.0f6c708f580494dbe96e4637823ed9b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712334
DOI:10.1186/s12879-022-07173-0