دورية أكاديمية
Pyroptosis: a double-edged sword in lung cancer and other respiratory diseases
| العنوان: | Pyroptosis: a double-edged sword in lung cancer and other respiratory diseases |
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| المؤلفون: | Xiao Liang, Ya Qin, Dan Wu, Qiong Wang, Hongshuai Wu |
| المصدر: | Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-10 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Cytology |
| مصطلحات موضوعية: | Pyroptosis, Caspase, Gasdermin, Lung cancer, Pneumonia, Medicine, Cytology, QH573-671 |
| الوصف: | Abstract Pyroptosis is an active cell death process mediated by gasdermin family proteins including Gasdermin A (GSDMA), Gasdermin B (GSDMB), Gasdermin C (GSDMC), Gasdermin D (GSDMD), Gasdermin E (GSDME, DFNA5), and DFNB59. Emerging evidences have shown that pyroptosis contributes to many pulmonary diseases, especially lung cancer, and pneumonia. The exact roles of pyroptosis and gasdermin family proteins are tremendously intricate. Besides, there are evidences that pyroptosis contributes to these respiratory diseases. However, it often plays a dual role in these diseases which is a cause for concern and makes it difficult for clinical translation. This review will focus on the multifaceted roles of pyroptosis in respiratory diseases. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1478-811X |
| Relation: | https://doaj.org/toc/1478-811X |
| DOI: | 10.1186/s12964-023-01458-w |
| URL الوصول: | https://doaj.org/article/0f9e6b3dc21e4e92bee208e5b13de4da |
| رقم الأكسشن: | edsdoj.0f9e6b3dc21e4e92bee208e5b13de4da |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1478811X |
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| DOI: | 10.1186/s12964-023-01458-w |