دورية أكاديمية
Pandemic (H1N1) 2009 Infection in Patients with Hematologic Malignancy
العنوان: | Pandemic (H1N1) 2009 Infection in Patients with Hematologic Malignancy |
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المؤلفون: | Catherine Liu, Brian S. Schwartz, Snigdha Vallabhaneni, Michael Nixon, Peter V. Chin-Hong, Steven A. Miller, Charles Y. Chiu, Lloyd Damon, W. Lawrence Drew |
المصدر: | Emerging Infectious Diseases, Vol 16, Iss 12, Pp 1910-1917 (2010) |
بيانات النشر: | Centers for Disease Control and Prevention, 2010. |
سنة النشر: | 2010 |
المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
مصطلحات موضوعية: | Pandemic (H1N1) 2009, viruses, hematologic malignancy, hematopoietic cell transplant, nosocomial transmission, oseltamivir resistance, Medicine, Infectious and parasitic diseases, RC109-216 |
الوصف: | To assess outcomes of patients with hematologic malignancy and pandemic (H1N1) 2009 infection, we reviewed cases during June–December 2009 at the University of California San Francisco Medical Center. Seventeen (63%) and 10 (37%) patients had upper respiratory tract infection (URTI) and lower respiratory tract infection (LRTI), respectively. Cough (85%) and fever (70%) were the most common signs; 19% of patients had nausea, vomiting, or diarrhea. Sixty-five percent of URTI patients were outpatients; 35% recovered without antiviral therapy. All LRTI patients were hospitalized; half required intensive care unit admission. Complications included acute respiratory distress syndrome, pneumomediastinum, myocarditis, and development of oseltamivir-resistant virus; 3 patients died. Of the 3 patients with nosocomial pandemic (H1N1) 2009, 2 died. Pandemic (H1N1) 2009 may cause serious illness in patients with hematologic malignancy, primarily those with LRTI. Rigorous infection control, improved techniques for diagnosing respiratory disease, and early antiviral therapy can prevent nosocomial transmission and optimize patient care. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1080-6040 1080-6059 |
Relation: | https://wwwnc.cdc.gov/eid/article/16/12/10-0772_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
DOI: | 10.3201/eid1612.100772 |
URL الوصول: | https://doaj.org/article/d10880e7db7d43e2b8295a568839202d |
رقم الأكسشن: | edsdoj.10880e7db7d43e2b8295a568839202d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 10806040 10806059 |
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DOI: | 10.3201/eid1612.100772 |