دورية أكاديمية
Immunolocalization of Nesfatin-1 in the Gastrointestinal Tract of the Common Bottlenose Dolphin Tursiops truncatus
| العنوان: | Immunolocalization of Nesfatin-1 in the Gastrointestinal Tract of the Common Bottlenose Dolphin Tursiops truncatus |
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| المؤلفون: | Elena De Felice, Claudia Gatta, Daniela Giaquinto, Federica Fioretto, Lucianna Maruccio, Danila d’Angelo, Paola Scocco, Paolo de Girolamo, Livia D’Angelo |
| المصدر: | Animals, Vol 12, Iss 16, p 2148 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Veterinary medicine LCC:Zoology |
| مصطلحات موضوعية: | Nesf-1, digestive tract, bottlenose dolphin, immunohistochemistry, Veterinary medicine, SF600-1100, Zoology, QL1-991 |
| الوصف: | First identified as an anorexigenic peptide, in the last decades, several studies have suggested that Nesfatin-1 (Nesf-1) is a pleiotropic hormone implicated in numerous regulatory processes in peripheral organs and tissues. In vertebrates, Nesf-1 is indeed expressed in the central nervous system and peripheral organs. In this study, we characterized the pattern of Nesf-1 distribution within the digestive tract of the common bottlenose dolphin (Tursiops truncatus), composed of three gastric chambers and an intestine without a clear subdivision in the small and large intestine, also lacking a caecum. Our results indicated that Nesf-1 is widely distributed in cells of the mucosal epithelium of the gastric chambers. Most of the immunoreactivity was observed in the second chamber, compared to the first and third chambers. Immunopositivity was also found in nerve fibers and neurons, scattered or/and clustered in ganglion structures along all the examined gastrointestinal tracts. These observations add new data on the highly conserved role of Nesf-1 in the mammalian digestive system. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-2615 |
| Relation: | https://www.mdpi.com/2076-2615/12/16/2148; https://doaj.org/toc/2076-2615 |
| DOI: | 10.3390/ani12162148 |
| URL الوصول: | https://doaj.org/article/10d2a1961d4d48bab991ca2504e1903e |
| رقم الأكسشن: | edsdoj.10d2a1961d4d48bab991ca2504e1903e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20762615 |
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| DOI: | 10.3390/ani12162148 |