دورية أكاديمية
Non-peptide compounds from Kronopolites svenhedini (Verhoeff) and their antitumor and iNOS inhibitory activities
| العنوان: | Non-peptide compounds from Kronopolites svenhedini (Verhoeff) and their antitumor and iNOS inhibitory activities |
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| المؤلفون: | Yuan-Nan Yuan, Jin-Qiang Li, Hong-Bin Fang, Shao-Jun Xing, Yong-Ming Yan, Yong-Xian Cheng |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 789-799 (2023) |
| بيانات النشر: | Beilstein-Institut, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | arthropod, inos, kronopolites svenhedini (verhoeff), non-peptide small molecules, Science, Organic chemistry, QD241-441 |
| الوصف: | Six new compounds, including a tetralone 1, two xanthones 2 and 3, a flavan derivative 4, and two nor-diterpenoids 7 and 8, accompanied by two known flavan derivatives 5 and 6 and a known olefine acid (9) were isolated from whole bodies of Kronopolites svenhedini (Verhoeff). The structures of the new compounds were determined by 1D and 2D nuclear magnetic resonance (NMR) and other spectroscopic methods, as well as computational methods. Selected compounds were evaluated for their biological properties against a mouse pancreatic cancer cell line and inhibitory effects on iNOS and COX-2 in RAW264.7 cells. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.19.59 |
| URL الوصول: | https://doaj.org/article/12c370a61c3543348e5ae8e883f516ed |
| رقم الأكسشن: | edsdoj.12c370a61c3543348e5ae8e883f516ed |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
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| DOI: | 10.3762/bjoc.19.59 |