دورية أكاديمية
Anthocyanins profiling of bilberry (Vaccinium myrtillus L.) extract that elucidates antioxidant and anti-inflammatory effects
| العنوان: | Anthocyanins profiling of bilberry (Vaccinium myrtillus L.) extract that elucidates antioxidant and anti-inflammatory effects |
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| المؤلفون: | Al Borhan Bayazid, Eun Mi Chun, Mohammad Al Mijan, Seo Hyun Park, Sung-Kwon Moon, Beong Ou Lim |
| المصدر: | Food and Agricultural Immunology, Vol 32, Iss 1, Pp 713-726 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Agriculture (General) LCC:Immunologic diseases. Allergy |
| مصطلحات موضوعية: | bilberry, anthocyanins, antioxidant, inflammations, raw 264.7 cells, lps, Agriculture (General), S1-972, Immunologic diseases. Allergy, RC581-607 |
| الوصف: | Bilberry (Vaccinium myrtillus L.) is a medicinal fruit known for its high content of anthocyanins, flavonoids, vitamins, ascorbic acid, carotenoids, tocopherols and phenolic acid. Bilberry has long been used in oriental medicine for the prevention and treatment of various diseases, such as visual acuity, hyperglycemia, dyslipidemia, diabetes, cancer, obesity, inflammatory and cardiovascular diseases. In this study, we investigated using the antioxidant and anti-inflammatory of 70% ethanol extracts of bilberry in vitro. Antioxidant activities were measured with total phenolic, flavonoid and ascorbic acid contents. The bilberry extract (BE) showed significant free radical scavenging activities and inhibited oxidation of linoleic acid in a dose-dependent manner. BE also suppressed nitric oxide (NO) generation and reversed pro-inflammatory cytokines such as iNOS, COX-2, TNF-α and IL-6 in LPS-induced RAW 264.7 cells. From these results, we suggest that BE is a natural powerful antioxidant, and the anti-inflammatory agent being a rich source of anthocyanins. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0954-0105 1465-3443 09540105 |
| Relation: | https://doaj.org/toc/0954-0105; https://doaj.org/toc/1465-3443 |
| DOI: | 10.1080/09540105.2021.1986471 |
| URL الوصول: | https://doaj.org/article/12ef84e3e5b94d45850c6ae260313a9e |
| رقم الأكسشن: | edsdoj.12ef84e3e5b94d45850c6ae260313a9e |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 09540105 14653443 |
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| DOI: | 10.1080/09540105.2021.1986471 |