دورية أكاديمية
Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals
| العنوان: | Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals |
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| المؤلفون: | María Esther Castillo, Carlos Bada, Olguita del Aguila, Verónica Petrozzi-Helasvuo, Verónica Casabona-Ore, Isabel Reyes, Juana del Valle-Mendoza |
| المصدر: | International Journal of Infectious Diseases, Vol 41, Iss C, Pp 36-41 (2015) |
| بيانات النشر: | Elsevier, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Bordetella pertussis, Whooping cough, PCR, Peru, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Objectives: To report the incidence, epidemiology, and clinical features of Bordetella pertussis in Peruvian infants under 1 year old. Patients and methods: A prospective cross-sectional study was conducted in five hospitals in Peru from January 2010 to July 2012. A total of 392 infants under 1 year old were admitted with a clinical diagnosis of whooping cough and tested for B. pertussis by PCR. Results: The pertussis toxin and IS481 genes were detected in 39.54% (155/392) of the cases. Infants aged less than 3 months were the most affected, with a prevalence of 73.55% (114/155). The most common household contact was the mother, identified in 20% (31/155) of cases. Paroxysm of coughing (89.03%, 138/155), cyanosis (68.39%, 106/155), respiratory distress (67.09%, 104/155), and breastfeeding difficulties (39.35%, 61/155) were the most frequent symptoms reported. Conclusion: An increase in pertussis cases has been reported in recent years in Peru, despite national immunization efforts. Surveillance with PCR for B. pertussis is essential, especially in infants less than 1 year old, in whom a higher rate of disease-related complications and higher mortality have been reported. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1201-9712 1878-3511 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1201971215002544; https://doaj.org/toc/1201-9712; https://doaj.org/toc/1878-3511 |
| DOI: | 10.1016/j.ijid.2015.10.020 |
| URL الوصول: | https://doaj.org/article/14866ca6b9134169a7187aaade174991 |
| رقم الأكسشن: | edsdoj.14866ca6b9134169a7187aaade174991 |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 12019712 18783511 |
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| DOI: | 10.1016/j.ijid.2015.10.020 |