دورية أكاديمية

Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds

التفاصيل البيبلوغرافية
العنوان: Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds
المؤلفون: Yingnan Yin, Andrew J. Petersen, Cheryl Soref, William D. Richards, Tenneille Ludwig, Seth Taapken, Erich Berndt, Su-Chun Zhang, Anita Bhattacharyya
المصدر: Stem Cell Research, Vol 34, Iss , Pp - (2019)
بيانات النشر: Elsevier, 2019.
سنة النشر: 2019
المجموعة: LCC:Biology (General)
مصطلحات موضوعية: Biology (General), QH301-705.5
الوصف: Seven human induced pluripotent stem cell (iPSC) lines were generated from fibroblasts from three neonatal individuals using non-integrative reprogramming. Most control iPSCs are derived from adults, so these iPSCs meet the need for control iPSCs from young individuals. Donors were from different ethnicities and these lines provide unique genetic profiles. All iPSCs have normal karyotypes, express stem cell markers, and exhibit pluripotency, as assessed by capacity to differentiate into three germ layers. These lines are valuable to study human development, as age-matched controls for disorder-specific iPSCs, and as platforms for gene editing to control for age and ethnicity. Keywords: Neonatal, Unaffected, Control iPSCs
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1873-5061
Relation: http://www.sciencedirect.com/science/article/pii/S1873506118303003; https://doaj.org/toc/1873-5061
DOI: 10.1016/j.scr.2018.101365
URL الوصول: https://doaj.org/article/14d549b791674065a43022148853b283
رقم الأكسشن: edsdoj.14d549b791674065a43022148853b283
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:18735061
DOI:10.1016/j.scr.2018.101365