دورية أكاديمية
Renal Infarction during Anticoagulant Therapy after Living Donor Liver Transplantation
| العنوان: | Renal Infarction during Anticoagulant Therapy after Living Donor Liver Transplantation |
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| المؤلفون: | Shinji Onda, Hiroaki Shiba, Yuki Takano, Kenei Furukawa, Taigo Hata, Katsuhiko Yanaga |
| المصدر: | Case Reports in Gastroenterology, Vol 12, Iss 1, Pp 165-169 (2018) |
| بيانات النشر: | Karger Publishers, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Renal infarction, Living donor liver transplantation, Anticoagulant therapy, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Introduction: Liver transplant recipients are at risk for complications of vascular thrombosis. The reconstructed hepatic artery and portal vein thrombosis potentially result in hepatic failure and graft loss. Renal infarction is a rare clinical condition, but in severe cases, it may lead to renal failure. We herein report a case of renal infarction after living donor liver transplantation (LDLT) during anticoagulant therapy. Case Presentation: A 60-year-old woman with end-stage liver disease due to primary biliary cholangitis underwent LDLT with splenectomy. Postoperatively, tacrolimus, mycophenolate mofetil, and steroid were used for initial immunosuppression therapy. On postoperative day (POD) 5, enhanced computed tomography (CT) revealed splenic vein thrombosis, and anticoagulant therapy with heparin followed by warfarin was given. Follow-up enhanced CT on POD 20 incidentally demonstrated right renal infarction. The patient’s renal function was unchanged and the arterial flow was good, and the splenic vein thrombosis resolved. At 4 months postoperatively, warfarin was discontinued, but she developed recurrent splenic vein thrombosis 11 months later, and warfarin was resumed. As of 40 months after transplantation, she discontinued warfarin and remains well without recurrence of splenic vein thrombosis or renal infarction. Conclusion: Renal infarction is a rare complication of LDLT. In this case, renal infarction was incidentally diagnosed during anticoagulant therapy and was successfully treated. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1662-0631 00048852 |
| Relation: | https://www.karger.com/Article/FullText/488526; https://doaj.org/toc/1662-0631 |
| DOI: | 10.1159/000488526 |
| URL الوصول: | https://doaj.org/article/14d67d4fd1a248a3815c6ea625f10c8a |
| رقم الأكسشن: | edsdoj.14d67d4fd1a248a3815c6ea625f10c8a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16620631 00048852 |
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| DOI: | 10.1159/000488526 |