دورية أكاديمية
Predictors of poor prognosis in patients with heat stroke
| العنوان: | Predictors of poor prognosis in patients with heat stroke |
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| المؤلفون: | Jae-Kwon Chun, Sangchun Choi, Hyuk-Hoon Kim, Hee Won Yang, Chang Seong Kim |
| المصدر: | Clinical and Experimental Emergency Medicine, Vol 6, Iss 4, Pp 345-350 (2019) |
| بيانات النشر: | The Korean Society of Emergency Medicine, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medical emergencies. Critical care. Intensive care. First aid |
| مصطلحات موضوعية: | heat stroke, prognosis, biomarkers, s100b protein, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
| الوصف: | Objective The predictors of poor prognosis in heat stroke (HS) remain unknown. This study investigated the predictive factors of poor prognosis in patients with HS. Methods Data were obtained and analyzed from the health records of patients diagnosed with heat illness at Ajou university hospital between January 2008 and December 2017. Univariate and multivariate analyses were performed to identify the independent predictors of poor prognosis. Results Thirty-six patients (median age, 54.5 years; 33 men) were included in the study. Poor prognosis was identified in 27.8% of the study population (10 patients). The levels of S100B protein, troponin I, creatinine, alanine aminotransferase, and serum lactate were statistically significant in the univariate analysis. Multiple regression analysis revealed that poor prognosis was significantly associated with an increased S100B protein level (odds ratio, 177.37; 95% confidence interval, 2.59 to 12,143.80; P=0.016). The S100B protein cut-off level for predicting poor prognosis was 0.610 μg/L (area under the curve, 0.906; 95% confidence interval, 0.00 to 1.00), with 86% sensitivity and 86% specificity. Conclusion An increased S100B protein level on emergency department admission is an independent prognostic factor of poor prognosis in patients with HS. Elevation of the S100B protein level represents a potential target for specific and prompt therapies in these patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2383-4625 21908141 |
| Relation: | http://www.ceemjournal.org/upload/pdf/ceem-18-081.pdf; https://doaj.org/toc/2383-4625 |
| DOI: | 10.15441/ceem.18.081 |
| URL الوصول: | https://doaj.org/article/153fad21908141b78711027039cee6ab |
| رقم الأكسشن: | edsdoj.153fad21908141b78711027039cee6ab |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23834625 21908141 |
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| DOI: | 10.15441/ceem.18.081 |