دورية أكاديمية
LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS
| العنوان: | LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS |
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| المؤلفون: | V. V. Burlyaev, А. Davydenko, V. F. Kornyushko, L. I. Russu, M. Mezentseva |
| المصدر: | Тонкие химические технологии, Vol 12, Iss 3, Pp 73-80 (2017) |
| بيانات النشر: | MIREA - Russian Technological University, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | idef0, glp, information support, preclinical studies, targeted therapy drugs, cancer cell, logical-information model, Chemistry, QD1-999 |
| الوصف: | The paper deals with laboratory preclinical studies of the impact of targeted anticancer drugs on the life of A-549 cell cultures of the cancer origin (lung carcinoma). Preclinical studies enable evaluating the effectiveness of targeted therapy drugs, possible contraindications and side effects in order to determine in future the scope of clinical trials and the possibility of performing them. It is proposed to develop information support of preclinical research. In this work the use of functional modeling technology for building a logic-information model in the category of IDEF0 is considered. For detailed elaboration of the model it is necessary to review step-by-step the whole research process. The necessity of creating the information support is connected to the tasks of structuring, storage and processing large amounts of experimental data. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2410-6593 2686-7575 |
| Relation: | https://www.finechem-mirea.ru/jour/article/view/96; https://doaj.org/toc/2410-6593; https://doaj.org/toc/2686-7575 |
| DOI: | 10.32362/2410-6593-2017-12-3-73-80 |
| URL الوصول: | https://doaj.org/article/c160439ed89447fc859bd78ebf066f2f |
| رقم الأكسشن: | edsdoj.160439ed89447fc859bd78ebf066f2f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24106593 26867575 |
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| DOI: | 10.32362/2410-6593-2017-12-3-73-80 |