دورية أكاديمية
Combining primary tumor features derived from conventional and contrast-enhanced ultrasound facilitates the prediction of positive axillary lymph nodes in Breast Imaging Reporting and Data System category 4 malignant breast lesions
| العنوان: | Combining primary tumor features derived from conventional and contrast-enhanced ultrasound facilitates the prediction of positive axillary lymph nodes in Breast Imaging Reporting and Data System category 4 malignant breast lesions |
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| المؤلفون: | Yu Du, Chun-Bei Yi, Li-Wen Du, Hai-Yan Gong, Li-Jun Ling, Xin-Hua Ye, Min Zong, Cui-Ying Li |
| المصدر: | Diagnostic and Interventional Radiology, Vol 29, Iss 3, Pp 469-477 (2023) |
| بيانات النشر: | Galenos Publishing House, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | conventional ultrasound, contrast enhanced ultrasound, bi-rads category, breast cancer, axillary lymph node metastasis, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | PURPOSETo determine whether the primary tumor features derived from conventional ultrasound (US) and contrast-enhanced US (CEUS) facilitate the prediction of positive axillary lymph nodes (ALNs) in breast cancer diagnosed as Breast Imaging Reporting and Data System (BI-RADS) category 4.METHODSA total of 240 women with breast cancer who underwent preoperative conventional US, strain elastography, and CEUS between September 2016 and December 2019 were included. The multiple parameters of the primary tumor were obtained, and univariate and multivariate analyses were performed to predict positive ALNs. Then three prediction models (conventional US features, CEUS features, and the combined features) were developed, and the diagnostic performance was evaluated with receiver operating characteristic curves.RESULTSOn conventional US, the traits of large size and the non-circumscribed margin of the primary tumor were marked as two independent predictors. On CEUS, the features of vessel perforation or distortion and the enhanced range of the primary tumor were marked as two independent predictors for positive ALNs. Three prediction models were then developed: model A (conventional US features), model B (CEUS features), and model C (model A plus B). Model C yielded the highest area under the curve (AUC) of 0.82 [95% confidence interval (CI), 0.75–0.88] compared with model A (AUC 0.74; 95% CI, 0.68–0.81; P = 0.008) and model B (AUC 0.72; 95% CI, 0.65–0.80; P < 0.001) as per the DeLong test.CONCLUSIONCEUS, as a non-invasive examination technique, can be used to predict ALN metastasis. Combining conventional US and CEUS may produce favorable predictive accuracy for positive ALNs in BI-RADS category 4 breast cancer. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1305-3825 1305-3612 |
| Relation: | http://www.dirjournal.org/archives/archive-detail/article-preview/combining-primary-tumor-features-derived-from-conv/57721; https://doaj.org/toc/1305-3825; https://doaj.org/toc/1305-3612 |
| DOI: | 10.4274/dir.2022.22534 |
| URL الوصول: | https://doaj.org/article/16c7784e6f334eb7aea612fcbb16189a |
| رقم الأكسشن: | edsdoj.16c7784e6f334eb7aea612fcbb16189a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13053825 13053612 |
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| DOI: | 10.4274/dir.2022.22534 |