دورية أكاديمية
Distinct Expression Profiles of Three Melatonin Receptors during Early Development and Metamorphosis in the Flatfish Solea senegalensis
| العنوان: | Distinct Expression Profiles of Three Melatonin Receptors during Early Development and Metamorphosis in the Flatfish Solea senegalensis |
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| المؤلفون: | Olivier Lan-Chow-Wing, Francesca Confente, Patricia Herrera-Pérez, Esther Isorna, Olvido Chereguini, Maria del Carmen Rendón, Jack Falcón, José A. Muñoz-Cueto |
| المصدر: | International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20789-20799 (2014) |
| بيانات النشر: | MDPI AG, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | melatonin receptors, development, metamorphosis, flatfish, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Melatonin actions are mediated through G protein-coupled transmembrane receptors. Recently, mt1, mt2, and mel1c melatonin receptors were cloned in the Senegalese sole. Here, their day-night and developmental expressions were analyzed by quantitative PCR. These results revealed distinct expression patterns of each receptor through development. mel1c transcripts were more abundant in unfertilized ovulated oocytes and declined during embryonic development. mt1 and mt2 expression was higher at the earliest stages (2–6 days post-fertilization), decreasing before (mt2) or during (mt1) metamorphosis. Only mt1 and mel1c expression exhibited day-night variations, with higher nocturnal mRNA levels. These results suggest different roles and transcriptional regulation of these melatonin receptors during flatfish development and metamorphosis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 |
| Relation: | http://www.mdpi.com/1422-0067/15/11/20789; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms151120789 |
| URL الوصول: | https://doaj.org/article/e16d2856dfe347078d6b151948a80198 |
| رقم الأكسشن: | edsdoj.16d2856dfe347078d6b151948a80198 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 |
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| DOI: | 10.3390/ijms151120789 |