دورية أكاديمية
Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020)
| العنوان: | Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020) |
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| المؤلفون: | Rachel Thommen, Christian A. Bowers, Aaron C. Segura, Joanna M. Roy, Meic H. Schmidt |
| المصدر: | Neurospine, Vol 21, Iss 2, Pp 404-413 (2024) |
| بيانات النشر: | Korean Spinal Neurosurgery Society, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | frailty, risk analysis index, spinal tumor, metastatic, spinal oncology, national surgical quality improvement program, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Objective To evaluate the prognostic utility of baseline frailty, measured by the Risk Analysis Index (RAI), for prediction of postoperative mortality among patients with spinal malignancy (SM) undergoing resection. Methods SM surgery cases were queried from the American College of Surgeons – National Surgical Quality Improvement Program database (2011–2020). The relationship between preoperative RAI frailty score and increasing rate of primary endpoint (mortality or discharge to hospice within 30 days, “mortality/hospice”) were assessed. Discriminatory accuracy was assessed by computation of C-statistics (with 95% confidence interval [CI]) in receiver operating characteristic (ROC) curve analysis. Results A total of 2,235 cases were stratified by RAI score: 0–20, 22.7%; 21–30, 11.9%; 31–40, 54.7%; and ≥ 41, 10.7%. The rate of mortality/hospice was 6.5%, which increased linearly with increasing RAI score (p < 0.001). RAI was also associated with increasing rates of major complication, extended length of stay, and nonhome discharge (all p < 0.05). The RAI demonstrated acceptable discriminatory accuracy for prediction of primary endpoint (C-statistic, 0.717; 95% CI, 0.697–0.735). In pairwise ROC comparison, RAI demonstrated superiority versus modified frailty index-5 and chronological age (p < 0.001). Conclusion Preoperative frailty, as measured by RAI, is a robust predictor of mortality/hospice after SM surgery. The frailty score may be applied in clinical settings using a user-friendly calculator, deployed here: https://nsgyfrailtyoutcomeslab.shinyapps.io/spinalMalignancyRAI/. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2586-6583 2586-6591 |
| Relation: | http://e-neurospine.org/upload/pdf/ns-2347120-560.pdf; https://doaj.org/toc/2586-6583; https://doaj.org/toc/2586-6591 |
| DOI: | 10.14245/ns.2347120.560 |
| URL الوصول: | https://doaj.org/article/e172901385c14620930be61bcd2b385c |
| رقم الأكسشن: | edsdoj.172901385c14620930be61bcd2b385c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25866583 25866591 |
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| DOI: | 10.14245/ns.2347120.560 |