Generation and characterization of PBMCs-derived human induced pluripotent stem cell (iPSC) line SDQLCHi051-A from an autism spectrum disorder patient with compound CHD8 gene mutations

التفاصيل البيبلوغرافية
العنوان:	Generation and characterization of PBMCs-derived human induced pluripotent stem cell (iPSC) line SDQLCHi051-A from an autism spectrum disorder patient with compound CHD8 gene mutations
المؤلفون:	Yuxuan Fan, Yue Li, Xiaomeng Yang, Haiyan Zhang, Bin Wang, Jingyun Guan, Jianen Gao, Xu Ma, Yi Liu
المصدر:	Stem Cell Research, Vol 69, Iss , Pp 103114- (2023)
بيانات النشر:	Elsevier, 2023.
سنة النشر:	2023
المجموعة:	LCC:Biology (General)
مصطلحات موضوعية:	Biology (General), QH301-705.5
الوصف:	CHD8 mutation is a case of genetic related autism spectrum disorder(ASD), In our research, We describe here the derivation of the iPSC line SDQLCHi051-A from a patient with autism spectrum disorder (ASD) due to two heterozygote mutations (c.6728G > A and c.3876 T > G) in the CHD8 gene. The resulting iPSC line has typical iPSCs characteristics, including pluripotency and trilineage differentiation hallmarks.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1873-5061
Relation:	http://www.sciencedirect.com/science/article/pii/S1873506123001009; https://doaj.org/toc/1873-5061
DOI:	10.1016/j.scr.2023.103114
URL الوصول:	https://doaj.org/article/17c69fa5f30d4777bcf18817b9f5a4af
رقم الأكسشن:	edsdoj.17c69fa5f30d4777bcf18817b9f5a4af
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	18735061
DOI:	10.1016/j.scr.2023.103114