دورية أكاديمية
أعرض في EDS

A longitudinal analysis of the relationship between serum uric acid and residual renal function loss in peritoneal dialysis patients

التفاصيل البيبلوغرافية
العنوان: A longitudinal analysis of the relationship between serum uric acid and residual renal function loss in peritoneal dialysis patients
المؤلفون: Chiehlun Yang, Xinxin Ma, Wenbo Zhao, Yanru Chen, Hongchun Lin, Dan Luo, Jun Zhang, Tanqi Lou, Yu Peng, Hui Peng
المصدر: Renal Failure, Vol 42, Iss 1, Pp 447-454 (2020)
بيانات النشر: Taylor & Francis Group, 2020.
سنة النشر: 2020
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: peritoneal dialysis, uric acid, residual renal function, end-stage renal disease, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Background Hyperuricemia occurs frequently in patients with continuous ambulatory peritoneal dialysis (CAPD). This study aimed to evaluate the impact of serum uric acid (UA) over time on residual renal function (RRF) loss in a cohort of patients with CAPD. Methods A total of 201 patients who started CAPD therapy between January 1, 2008 and April 30, 2016 were included in this single-center, retrospective cohort study. All patients were followed up until December 31, 2016. The median follow-up time was 23.43 ± 16.60 months. RRF loss was represented as the time to anuria. Results Eighty-six patients developed anuria within 5 years. Multivariate Cox regression analysis showed that time-averaged serum UA and peritonitis were independent risk factors for RRF loss, while weekly Kt/V urea was a protective factor. Cox proportional hazard regression models showed that both patients with time-averaged uric acid (TA-UA) < 6.77 mg/dL [hazard ratio (HR) = 1.165, 95% confidence interval (CI) 1.054–1.387; p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0886-022X
1525-6049
0886022X
Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049
DOI: 10.1080/0886022X.2020.1761387
URL الوصول: https://doaj.org/article/196498917d6244acb60dd9109ec0013c
رقم الأكسشن: edsdoj.196498917d6244acb60dd9109ec0013c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:0886022X
15256049
DOI:10.1080/0886022X.2020.1761387