دورية أكاديمية
Estimation Activity And Partial Purification Of Leucine Amino Peptidase (Lap) In Patients Wiith Diabetic Nephropathy
| العنوان: | Estimation Activity And Partial Purification Of Leucine Amino Peptidase (Lap) In Patients Wiith Diabetic Nephropathy |
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| المؤلفون: | Baghdad Science Journal |
| المصدر: | Baghdad Science Journal, Vol 9, Iss 4 (2012) |
| بيانات النشر: | College of Science for Women, University of Baghdad, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Science |
| مصطلحات موضوعية: | |
| الوصف: | Leucine aminopepotidase (LAP)[EC:3.4.11.1] activity has been assayed in (50) serum samples of patients with diabeties naphrophathy D.N (non-insulin dependent diabetic (NIDD) , and (50)serum sample of healthy individuals without any clinically detectable diseases have been as control group. The aim of this study is to measure leucine aminopeptidase activity and partially purifying the enzyme from sera of patients with diabetes nephropathy The results of this study revealed that Leucine aminopeptidase (LAP) activity of nephropathy patient’s serum shows a high signifiacant increase (p < 0.001) compared to that of the healthy subjects.LAP was purified from the serum of patients with diabetes nephropathy by dialysis and gel filtration (Sephadex G-25) (fine ) (20 × 1.5 cm ) .A (1.37) fold purification of serum LAP from patients serum with diabetic nephropathy was achieved by using dialysis and this enzyme showed single grade increased to (8.33) fold by using gel filtration Abbreviation: Leucine aminopeptidase=LAP, Diabetes Nephropathy= D.N, Non- Insulin dependent diabetic= NIDD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Arabic English |
| تدمد: | 2078-8665 2411-7986 |
| Relation: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1414; https://doaj.org/toc/2078-8665; https://doaj.org/toc/2411-7986 |
| DOI: | 10.21123/bsj.9.4.689-694 |
| URL الوصول: | https://doaj.org/article/1a1a2341d4c44e1cb2b8ce5a2260e783 |
| رقم الأكسشن: | edsdoj.1a1a2341d4c44e1cb2b8ce5a2260e783 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20788665 24117986 |
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| DOI: | 10.21123/bsj.9.4.689-694 |