التفاصيل البيبلوغرافية
العنوان:
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML
المؤلفون:
Arvind Singh Mer , Emily M. Heath , Seyed Ali Madani Tonekaboni , Nergiz Dogan-Artun , Sisira Kadambat Nair , Alex Murison , Laura Garcia-Prat , Liran Shlush , Rose Hurren , Veronique Voisin , Gary D. Bader , Corey Nislow , Mattias Rantalainen , Soren Lehmann , Mark Gower , Cynthia J. Guidos , Mathieu Lupien , John E. Dick , Mark D. Minden , Aaron D. Schimmer , Benjamin Haibe-Kains
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Molecular heterogeneity of acute myeloid leukaemia (AML) across patients is a major challenge for prognosis and therapy. Here, the authors show that NPM1 mutated AML is a heterogeneous class, consisting of two subtypes which exhibit distinct molecular characteristics, differentiation state, patient survival and drug response.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-021-21233-0
URL الوصول:
https://doaj.org/article/a1a1fb4ad66d4a54b1ec1c09785a2551
رقم الأكسشن:
edsdoj.1a1fb4ad66d4a54b1ec1c09785a2551
قاعدة البيانات:
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