دورية أكاديمية
Reproductive indices in malaria infested mice treated with antimalarials, Phyllanthus amarus combined with vitamins
| العنوان: | Reproductive indices in malaria infested mice treated with antimalarials, Phyllanthus amarus combined with vitamins |
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| المؤلفون: | Matthew Obaineh Ojezele, Ighodaro Igbe, Agbonlahor Okhuarobo |
| المصدر: | Bulletin of Faculty of Pharmacy Cairo University, Vol 56, Iss 2, Pp 179-184 (2018) |
| بيانات النشر: | Faculty of Pharmacy, Cairo University, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Therapeutics. Pharmacology LCC:Pharmacy and materia medica LCC:Pharmaceutical industry |
| مصطلحات موضوعية: | Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441, Pharmaceutical industry, HD9665-9675 |
| الوصف: | Malaria disease is caused by the plasmodium organism transmitted into humans by the female anopheles mosquito. The effect of chloroquine, artesunate or Phyllantus amarus alone or combined with vitamins A, B, C or K on male fertility indices has received no attention. Hence this study was designed to investigate the effect of chloroquine, artesunate or seed extract of Phyllanthus amarus with or without vitamins A, B, C or E on testosterone levels, sperm motility, morphology, viability and count in mice infected with Plasmodium berghei. Four days following inoculation of adult male mice with Plasmodium berghei, the mice were treated with artesunate, chloroquine or Phyllanthus amarus seed extract alone or in combination with vitamins A, B, C or E once daily. Thereafter the mice were sacrificed and semen was collected for the determination of sperm count, motility, morphology and viability and blood sample collected for the determination of serum testosterone level by standardized methods. Treatment with chloroquine, artesunate or Phyllanthus amarus seed extract with or without vitamins A, B, C or E caused a significant (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1110-0931 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1110093118300358; https://doaj.org/toc/1110-0931 |
| DOI: | 10.1016/j.bfopcu.2018.10.004 |
| URL الوصول: | https://doaj.org/article/d1a45d5df7b54cb1b45854a292f82c62 |
| رقم الأكسشن: | edsdoj.1a45d5df7b54cb1b45854a292f82c62 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 11100931 |
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| DOI: | 10.1016/j.bfopcu.2018.10.004 |