دورية أكاديمية
Case series of ovarian neuroendocrine carcinoma: overview of clinicopathological features
| العنوان: | Case series of ovarian neuroendocrine carcinoma: overview of clinicopathological features |
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| المؤلفون: | Bao-Jie Feng, Tian-Hua Li, Yue-Hong Li, Jing-Xuan Feng, Jun Zhang, Jun-Ying Ma, Yan-Wei Wang, Su-Shuang Lu |
| المصدر: | BMC Women's Health, Vol 23, Iss 1, Pp 1-8 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Gynecology and obstetrics LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Immunohistochemistry, Neuroendocrine carcinoma, Ovary, Pathological characteristics, Prognosis, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270 |
| الوصف: | Abstract Background Ovarian neuroendocrine carcinoma (O-NEC) is a relatively uncommon neoplasm, and the current knowledge regarding its diagnosis and management is limited. In this series, our objective was to provide an overview of the clinicopathological characteristics of the disease by analyzing clinical case data to establish a theoretical foundation for the diagnosis and management of O-NEC. Case presentation We included three patients in the present case series, all of whom were diagnosed with primary O-NEC based on pathomorphological observation and immunohistochemistry. Patient 1 was a 62-year-old patient diagnosed with small cell carcinoma (SCC) of the pulmonary type. Post-surgery, the patient was diagnosed with stage II SCC of the ovary and underwent standardized chemotherapy; however, imaging examinations conducted at the 16-month follow-up revealed the existence of lymph node metastasis. Unfortunately, she passed away 21 months after the surgery. The other two patients were diagnosed with carcinoid tumors, one at age 39 and the other at age 71. Post-surgery, patient 2 was diagnosed with a carcinoid in the left ovary, whereas patient 3 was diagnosed with a carcinoid in her right ovary based on clinical evaluation. Neither of the cases received adjuvant therapy following surgery; however, they have both survived for 9 and 10 years, respectively, as of date. Conclusion Primary O-NECs are rare and of diverse histological types, each of which has its own unique biological features and prognosis. SCC is a neoplasm characterized by high malignancy and a poor prognosis, whereas carcinoid tumors are of lesser malignancy and have a more favorable prognosis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1472-6874 |
| Relation: | https://doaj.org/toc/1472-6874 |
| DOI: | 10.1186/s12905-023-02722-4 |
| URL الوصول: | https://doaj.org/article/1ace317413db473cbeb755e8ea0635c8 |
| رقم الأكسشن: | edsdoj.1ace317413db473cbeb755e8ea0635c8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14726874 |
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| DOI: | 10.1186/s12905-023-02722-4 |